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Quality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, July 2016
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Mentioned by

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3 tweeters
facebook
1 Facebook page

Citations

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8 Dimensions

Readers on

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41 Mendeley
Title
Quality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related
Published in
International Journal of Chronic Obstructive Pulmonary Disease, July 2016
DOI 10.2147/copd.s107303
Pubmed ID
Authors

Sharina Kort, Kirsten Ter Huurne, Job van der Palen, Wendy van Beurden, Kris Movig, Paul van der Valk, Marjolein Brusse-Keizer

Abstract

Poor adherence to inhaled medications in COPD patients seems to be associated with an increased risk of death and hospitalization. Knowing the determinants of nonadherence to inhaled medications is important for creating interventions to improve adherence. To identify disease-specific and health-related quality of life (HRQoL) factors, associated with adherence to inhaled corticosteroids (ICS) and tiotropium in COPD patients. Adherence of 795 patients was recorded over 3 years and was deemed optimal at >75%-≤125%, suboptimal at ≥50%-<75%, and poor at <50% (underuse) or >125% (overuse). Health-related quality of life was measured with the Clinical COPD Questionnaire and the EuroQol-5D questionnaire. Patients with a higher forced expiratory volume in 1 second (FEV1)/vital capacity (VC) (odds ratio [OR] =1.03) and ≥1 hospitalizations in the year prior to inclusion in this study (OR =2.67) had an increased risk of suboptimal adherence to ICS instead of optimal adherence. An increased risk of underuse was predicted by a higher FEV1/VC (OR =1.05). Predictors for the risk of overuse were a lower FEV1 (OR =0.49), higher scores on Clinical COPD Questionnaire-question 3 (anxiety for dyspnea) (OR =1.26), and current smoking (OR =1.73). Regarding tiotropium, predictors for suboptimal use were a higher FEV1/VC (OR =1.03) and the inability to perform usual activities as asked by the EuroQol-5D questionnaire (OR =3.09). A higher FEV1/VC also was a predictor for the risk of underuse compared to optimal adherence (OR =1.03). The risk of overuse increased again with higher scores on Clinical COPD Questionnaire-question 3 (OR =1.46). Several disease-specific and quality of life factors are related to ICS and tiotropium adherence, but a clear profile of a nonadherent patient cannot yet be outlined. Overusers of ICS and tiotropium experience more anxiety.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 22%
Researcher 8 20%
Other 5 12%
Student > Bachelor 4 10%
Student > Ph. D. Student 4 10%
Other 4 10%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 19 46%
Nursing and Health Professions 7 17%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Psychology 2 5%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 8 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2016.
All research outputs
#4,107,176
of 8,603,451 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#547
of 1,108 outputs
Outputs of similar age
#120,331
of 262,042 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#47
of 93 outputs
Altmetric has tracked 8,603,451 research outputs across all sources so far. This one has received more attention than most of these and is in the 50th percentile.
So far Altmetric has tracked 1,108 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,042 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.