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Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series

Overview of attention for article published in Journal of Pain Research, October 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#50 of 1,336)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
4 news outlets
twitter
27 tweeters
patent
5 patents
facebook
13 Facebook pages
googleplus
1 Google+ user
video
1 video uploader

Citations

dimensions_citation
56 Dimensions

Readers on

mendeley
141 Mendeley
Title
Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series
Published in
Journal of Pain Research, October 2012
DOI 10.2147/jpr.s32143
Pubmed ID
Authors

Jan Keppel Hesselink, Hekker

Abstract

Palmitoylethanolamide (PEA), an endogenous fatty acid amide, has been demonstrated to bind to a receptor in the cell nucleus - the peroxisome proliferator-activated receptor - and performs a great variety of biological functions related to chronic and neuropathic pain and inflammation, as has been demonstrated in clinical trials. These include peripheral neuropathies such as diabetic neuropathy, chemotherapy-induced peripheral neuropathy, carpal tunnel syndrome, sciatic pain, osteoarthritis, low-back pain, failed back surgery syndrome, dental pains, neuropathic pain in stroke and multiple sclerosis, chronic pelvic pain, postherpetic neuralgia, and vaginal pains. Probably due to the fact that PEA is an endogenous modulator as well as a compound in food, such as eggs and milk, no serious side effects have been reported, nor have drug-drug interactions. This article presents a case series describing the application and potential efficacy and safety of PEA in the treatment of various syndromes associated with chronic pain that is poorly responsive to standard therapies.

Twitter Demographics

The data shown below were collected from the profiles of 27 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 1%
United States 1 <1%
Denmark 1 <1%
Spain 1 <1%
Unknown 136 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 33 23%
Researcher 25 18%
Student > Master 25 18%
Student > Ph. D. Student 17 12%
Student > Postgraduate 5 4%
Other 25 18%
Unknown 11 8%
Readers by discipline Count As %
Medicine and Dentistry 58 41%
Nursing and Health Professions 15 11%
Neuroscience 11 8%
Pharmacology, Toxicology and Pharmaceutical Science 9 6%
Agricultural and Biological Sciences 9 6%
Other 22 16%
Unknown 17 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 69. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2021.
All research outputs
#381,934
of 17,816,628 outputs
Outputs from Journal of Pain Research
#50
of 1,336 outputs
Outputs of similar age
#2,401
of 162,429 outputs
Outputs of similar age from Journal of Pain Research
#1
of 14 outputs
Altmetric has tracked 17,816,628 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,336 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,429 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.