Title |
The effect of <em>Helicobacter pylori</em> on asthma and allergy
|
---|---|
Published in |
Journal of Asthma and Allergy, September 2010
|
DOI | 10.2147/jaa.s8971 |
Pubmed ID | |
Authors |
Amedeo Amedei, Gaia Codolo, Gianfranco Del Prete, Marina de Bernard, Mario M D’Elios |
Abstract |
Current evidence indicates an inverse association between Helicobacter pylori and asthma and allergy. H. pylori is a Gram-negative bacterium which represents the major cause of peptic ulcer and gastric cancer, and preferentially elicits a T helper (Th)-1 response. Many H. pylori factors, such as the neutrophil-activating factor of H. pylori (HP-NAP), are able to drive Th-1 polarization and to display a powerful inhibition of allergic Th-2 response. This article proposes an overview of the actual knowledge about the effects of H. pylori on asthma and allergy. Special attention has been drawn to HP-NAP as a potential novel strategy for the prevention and treatment of asthma and atopy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | 20% |
United States | 2 | 20% |
Unknown | 6 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Unknown | 42 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 23% |
Student > Ph. D. Student | 9 | 21% |
Student > Bachelor | 9 | 21% |
Professor | 3 | 7% |
Student > Postgraduate | 2 | 5% |
Other | 7 | 16% |
Unknown | 3 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 33% |
Agricultural and Biological Sciences | 11 | 26% |
Immunology and Microbiology | 5 | 12% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 4 | 9% |
Unknown | 5 | 12% |