| Title |
A magnetic resonance (MR) compatible selective brain temperature manipulation system for preclinical study
|
|---|---|
| Published in |
Medical Devices : Evidence and Research, March 2012
|
| DOI | 10.2147/mder.s26835 |
| Pubmed ID | |
| Authors |
Qingwei Liu, Yu Cai, Weili Lin, Gregory H Turner, Hongyu An |
| Abstract |
There is overwhelming evidence that hypothermia can improve the outcome of an ischemic stroke. However, the most widely used systemic cooling method could lead to multiple side effects, while the incompatibility with magnetic resonance imaging of the present selective cooling methods highly limit their application in preclinical studies. In this study, we developed a magnetic resonance compatible selective brain temperature manipulation system for small animals, which can regulate brain temperature quickly and accurately for a desired period of time, while maintaining the normal body physiological conditions. This device was utilized to examine the relationship between T1 relaxation, cerebral blood flow, and temperature in brain tissue during magnetic resonance imaging of ischemic stroke. The results showed that this device can be an efficient brain temperature manipulation tool for preclinical studies needing local hypothermic or hyperthermic conditions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 7% |
| Unknown | 14 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 20% |
| Researcher | 2 | 13% |
| Student > Master | 2 | 13% |
| Lecturer | 1 | 7% |
| Professor | 1 | 7% |
| Other | 3 | 20% |
| Unknown | 3 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 27% |
| Neuroscience | 3 | 20% |
| Sports and Recreations | 1 | 7% |
| Nursing and Health Professions | 1 | 7% |
| Physics and Astronomy | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 4 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2013.
All research outputs
#17,348,622
of 25,457,858 outputs
Outputs from Medical Devices : Evidence and Research
#193
of 314 outputs
Outputs of similar age
#110,606
of 168,355 outputs
Outputs of similar age from Medical Devices : Evidence and Research
#2
of 3 outputs
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