| Title |
Type 2 diabetes mellitus might be a risk factor for mild cognitive impairment progressing to Alzheimer’s disease
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, September 2016
|
| DOI | 10.2147/ndt.s111298 |
| Pubmed ID | |
| Authors |
Wei Li, Tao Wang, Shifu Xiao |
| Abstract |
Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD), so identification of the related risk factors can be helpful. Although the association between type 2 diabetes mellitus (T2DM) and these modest changes in cognition is well established, whether T2DM will promote the transformation of MCI into AD is not a unified conclusion. This study aims to explore the relationship between T2DM and MCI in the elderly population living in the community in Shanghai, People's Republic of China. A total of 197 participants were included in the study. They were screened for T2DM, hyperlipidemia, traumatic brain injury, and family history of dementia. The Mini-Mental State Examination and the Montreal Cognitive Assessment were used to assess cognitive function. The diagnosis of AD was made according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, whereas the diagnosis of MCI was made according to Petersen's criteria. Then, we investigated the relation between T2DM and MCI. A total of 82 (41.6%) participants had no cognitive impairment, 82 (41.6%) participants had MCI, and 33 (16.8%) participants had AD. Multivariate logistic regression models demonstrated that T2DM was a risk factor for AD (odds ratio =49.723, 95% CI =21.173-111.987). T2DM might be a risk factor for MCI progressing into AD. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 100 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 19% |
| Student > Ph. D. Student | 12 | 12% |
| Researcher | 11 | 11% |
| Student > Master | 8 | 8% |
| Student > Doctoral Student | 7 | 7% |
| Other | 18 | 18% |
| Unknown | 27 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 19% |
| Nursing and Health Professions | 14 | 14% |
| Psychology | 12 | 12% |
| Neuroscience | 11 | 11% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Other | 12 | 12% |
| Unknown | 28 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2016.
All research outputs
#3,450,818
of 25,576,275 outputs
Outputs from Neuropsychiatric Disease and Treatment
#497
of 3,141 outputs
Outputs of similar age
#56,192
of 348,941 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#27
of 104 outputs
Altmetric has tracked 25,576,275 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,141 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,941 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.