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Superior antidepressant effect occurring 1 month after rTMS: add-on rTMS for subjects with medication-resistant depression

Overview of attention for article published in Neuropsychiatric Disease and Treatment, March 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Citations

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52 Mendeley
Title
Superior antidepressant effect occurring 1 month after rTMS: add-on rTMS for subjects with medication-resistant depression
Published in
Neuropsychiatric Disease and Treatment, March 2013
DOI 10.2147/ndt.s40466
Pubmed ID
Authors

Shaw-Ji Chen, Chung-Hung Chang, Hsin-Chi Tsai, Shao-Tsu Chen, Chaucer CH Lin

Abstract

Depression is a major psychiatric disorder. The standard treatment for depression is antidepressant medication, but the responses to antidepressant treatment are only partial, even poor, among 30%-45% of patients. Refractory depression is defined as depression that does not respond to antidepressant therapy after 4 weeks of use. There is evidence that repetitive transcranial magnetic stimulation (rTMS) may exert effects in treating psychiatric disorder through moderating focal neuronal functions. High-frequency rTMS on the left prefrontal area and low-frequency rTMS on the right prefrontal area were shown to be effective in alleviating depressive symptoms. Given the statistically significant antidepressant effectiveness noted, the clinical application of rTMS as a depression treatment warrants further studies. Application of rTMS as an add-on therapy would be a practical research model. High-frequency (5-20 Hz) rTMS over the left dorsolateral prefrontal cortex was found to have a significant effect on medication-resistant depression. In the present study, we not only measured the acute antidepressant effect of rTMS during treatment and immediately after its completion but also evaluated participants 1 month after completion of the treatment protocol. Study participants were divided into two groups: an active rTMS group (n = 10) and a sham group (n = 10). The active rTMS group was defined as participants who received the rTMS protocol, and the sham group was defined as participants who received a sham rTMS procedure. A significant Hamilton Depression Rating Scale score reduction was observed in both groups after the fifth and tenth treatments. However, those in the active rTMS group maintained their improvement as measured one month after completion of the rTMS protocol. Participants who received active rTMS were more likely to have persistent improvement in depression scores than participants who received sham rTMS.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Germany 1 2%
Unknown 50 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 27%
Student > Master 5 10%
Researcher 4 8%
Other 4 8%
Student > Postgraduate 4 8%
Other 7 13%
Unknown 14 27%
Readers by discipline Count As %
Medicine and Dentistry 15 29%
Psychology 6 12%
Agricultural and Biological Sciences 4 8%
Neuroscience 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 5 10%
Unknown 17 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2019.
All research outputs
#7,960,512
of 25,374,647 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,035
of 3,132 outputs
Outputs of similar age
#63,865
of 206,326 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#13
of 44 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,326 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.