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Coenzyme Q10 effects in neurodegenerative disease

Overview of attention for article published in Neuropsychiatric Disease and Treatment, November 2009
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
41 X users
facebook
1 Facebook page
video
2 YouTube creators

Citations

dimensions_citation
158 Dimensions

Readers on

mendeley
208 Mendeley
Title
Coenzyme Q10 effects in neurodegenerative disease
Published in
Neuropsychiatric Disease and Treatment, November 2009
DOI 10.2147/ndt.s5212
Pubmed ID
Authors

Meredith Spindler, M Flint Beal, Claire Henchcliffe

Abstract

Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial respiratory chain, and as a dietary supplement it has recently gained attention for its potential role in the treatment of neurodegenerative disease. Evidence for mitochondrial dysfunction in neurodegenerative disorders derives from animal models, studies of mitochondria from patients, identification of genetic defects in patients with neurodegenerative disease, and measurements of markers of oxidative stress. Studies of in vitro models of neuronal toxicity and animal models of neurodegenerative disorders have demonstrated potential neuroprotective effects of CoQ10. With this data in mind, several clinical trials of CoQ10 have been performed in Parkinson's disease and atypical Parkinson's syndromes, Huntington's disease, Alzheimer disease, Friedreich's ataxia, and amyotrophic lateral sclerosis, with equivocal findings. CoQ10 is widely available in multiple formulations and is very well tolerated with minimal adverse effects, making it an attractive potential therapy. Phase III trials of high-dose CoQ10 in large sample sizes are needed to further ascertain the effects of CoQ10 in neurodegenerative diseases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Italy 1 <1%
Germany 1 <1%
Egypt 1 <1%
India 1 <1%
Unknown 201 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 15%
Student > Bachelor 31 15%
Researcher 23 11%
Student > Master 21 10%
Other 15 7%
Other 45 22%
Unknown 41 20%
Readers by discipline Count As %
Medicine and Dentistry 43 21%
Agricultural and Biological Sciences 30 14%
Pharmacology, Toxicology and Pharmaceutical Science 22 11%
Biochemistry, Genetics and Molecular Biology 18 9%
Neuroscience 18 9%
Other 34 16%
Unknown 43 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2024.
All research outputs
#949,989
of 25,593,129 outputs
Outputs from Neuropsychiatric Disease and Treatment
#124
of 3,138 outputs
Outputs of similar age
#2,471
of 109,069 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#2
of 7 outputs
Altmetric has tracked 25,593,129 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,138 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,069 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.