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Symptom variability in COPD: a narrative review

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, May 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

twitter
6 tweeters
facebook
2 Facebook pages

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
79 Mendeley
Title
Symptom variability in COPD: a narrative review
Published in
International Journal of Chronic Obstructive Pulmonary Disease, May 2013
DOI 10.2147/copd.s42866
Pubmed ID
Authors

Jose Lopez-Campos, Calero, Quintana-Gallego

Abstract

Chronic obstructive pulmonary disease (COPD) has traditionally been considered an inexorably progressive disease, associated with a constant increase of symptoms that occur as the forced expiratory volume in 1 second (FEV1) worsens, only intermittently interrupted by exacerbations. However, this paradigm has been challenged in recent decades by the available evidence. Recent studies have pointed out that COPD-related symptoms are not consistently perceived by patients in the same way, showing not only seasonal variation, but also changes in symptom perception during a week or even within a single day. According to the available data, patients experience the biggest increase in respiratory symptoms during the first hours of the early morning, followed by the nighttime. This variation over time is of considerable importance, since it impacts on daily life activities and health-related quality of life, as measured by a recently developed ad hoc questionnaire. Additionally, recent clinical trials have suggested that the use of rapid-onset long-acting bronchodilators may have an impact on morning symptoms, despite their current use as maintenance treatment for a determined period. Although this hypothesis is to be validated in future long-term clinical trials comparing fast-onset versus slow-onset inhaled drugs in COPD, it may bring forward a new concept of long-term bronchodilator therapy. At the present time, the two available long-acting, fast-onset bronchodilators used in the treatment of COPD are formoterol and the recently marketed indacaterol. Newer drugs have also been shown to have a rapid onset of action in preclinical studies. Health care professionals caring for COPD patients should consider this variation in the perception of symptoms during their clinical interview as a potential new target in the long-term treatment plan.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
India 1 1%
Portugal 1 1%
Canada 1 1%
Unknown 75 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 19%
Student > Ph. D. Student 13 16%
Student > Master 8 10%
Student > Bachelor 7 9%
Student > Doctoral Student 6 8%
Other 23 29%
Unknown 7 9%
Readers by discipline Count As %
Medicine and Dentistry 44 56%
Nursing and Health Professions 6 8%
Agricultural and Biological Sciences 5 6%
Computer Science 3 4%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 12 15%
Unknown 7 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2013.
All research outputs
#2,880,019
of 11,344,729 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#358
of 1,313 outputs
Outputs of similar age
#32,168
of 130,376 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#7
of 20 outputs
Altmetric has tracked 11,344,729 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,313 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,376 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.