Title |
The physiology of cardiovascular disease and innovative liposomal platforms for therapy
|
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Published in |
International Journal of Nanomedicine, February 2013
|
DOI | 10.2147/ijn.s30599 |
Pubmed ID | |
Authors |
Guillermo U Ruiz-Esparza, Jose H Flores-Arredondo, Victor Segura-Ibarra, Guillermo Torre-Amione, Mauro Ferrari, Elvin Blanco, Rita E Serda |
Abstract |
Heart disease remains the major cause of death in males and females, emphasizing the need for novel strategies to improve patient treatment and survival. A therapeutic approach, still in its infancy, is the development of site-specific drug-delivery systems. Nanoparticle-based delivery systems, such as liposomes, have evolved into robust platforms for site-specific delivery of therapeutics. In this review, the clinical impact of cardiovascular disease and the pathophysiology of different subsets of the disease are described. Potential pathological targets for therapy are introduced, and promising advances in nanotherapeutic cardiovascular applications involving liposomal platforms are presented. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Poland | 1 | 1% |
Unknown | 95 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 16 | 16% |
Student > Bachelor | 13 | 13% |
Student > Master | 12 | 12% |
Researcher | 9 | 9% |
Student > Postgraduate | 5 | 5% |
Other | 16 | 16% |
Unknown | 26 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 16% |
Biochemistry, Genetics and Molecular Biology | 15 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 10% |
Agricultural and Biological Sciences | 7 | 7% |
Chemistry | 5 | 5% |
Other | 17 | 18% |
Unknown | 27 | 28% |