| Title |
Mesoporous silica nanoparticles for stimuli-responsive controlled drug delivery: advances, challenges, and outlook
|
|---|---|
| Published in |
International Journal of Nanomedicine, December 2016
|
| DOI | 10.2147/ijn.s117495 |
| Pubmed ID | |
| Authors |
Yuanhui Song, Yihong Li, Qien Xu, Zhe Liu |
| Abstract |
With the development of nanotechnology, the application of nanomaterials in the field of drug delivery has attracted much attention in the past decades. Mesoporous silica nanoparticles as promising drug nanocarriers have become a new area of interest in recent years due to their unique properties and capabilities to efficiently entrap cargo molecules. This review describes the latest advances on the application of mesoporous silica nanoparticles in drug delivery. In particular, we focus on the stimuli-responsive controlled release systems that are able to respond to intracellular environmental changes, such as pH, ATP, GSH, enzyme, glucose, and H2O2. Moreover, drug delivery induced by exogenous stimuli including temperature, light, magnetic field, ultrasound, and electricity is also summarized. These advanced technologies demonstrate current challenges, and provide a bright future for precision diagnosis and treatment. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 254 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 254 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 49 | 19% |
| Student > Ph. D. Student | 42 | 17% |
| Researcher | 25 | 10% |
| Student > Bachelor | 21 | 8% |
| Student > Doctoral Student | 11 | 4% |
| Other | 31 | 12% |
| Unknown | 75 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 34 | 13% |
| Biochemistry, Genetics and Molecular Biology | 25 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 9% |
| Engineering | 19 | 7% |
| Agricultural and Biological Sciences | 17 | 7% |
| Other | 45 | 18% |
| Unknown | 91 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2023.
All research outputs
#5,240,751
of 25,374,917 outputs
Outputs from International Journal of Nanomedicine
#476
of 4,122 outputs
Outputs of similar age
#94,057
of 416,453 outputs
Outputs of similar age from International Journal of Nanomedicine
#11
of 75 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,122 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,453 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.