Title |
Preparation and evaluation of a multimodal minoxidil microemulsion versus minoxidil alone in the treatment of androgenic alopecia of mixed etiology: a pilot study
|
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Published in |
Drug Design, Development and Therapy, May 2013
|
DOI | 10.2147/dddt.s43481 |
Pubmed ID | |
Authors |
Farouk M Sakr, Ali MI Gado, Haseebur R Mohammed, Abdel Nasser Ismail Adam |
Abstract |
The variable success of topical minoxidil in the treatment of androgenic alopecia has led to the hypothesis that other pathways could mediate this form of hair loss, including infection and/or microinflammation of the hair follicles. In this study, we prepared a multimodal microemulsion comprising minoxidil (a dihydrotestosterone antagonist), diclofenac (a nonsteroidal anti-inflammatory agent), and tea tree oil (an anti-infective agent). We investigated the stability and physicochemical properties of this formulation, and its therapeutic efficacy compared with a formulation containing minoxidil alone in the treatment of androgenic alopecia. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 1% |
Unknown | 88 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 17% |
Researcher | 14 | 16% |
Student > Bachelor | 10 | 11% |
Student > Ph. D. Student | 10 | 11% |
Other | 4 | 4% |
Other | 13 | 15% |
Unknown | 23 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 16 | 18% |
Chemistry | 5 | 6% |
Agricultural and Biological Sciences | 3 | 3% |
Psychology | 3 | 3% |
Other | 14 | 16% |
Unknown | 28 | 31% |