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Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry

Overview of attention for article published in International Journal of Nanomedicine, January 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (58th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
2 tweeters
googleplus
1 Google+ user

Citations

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56 Dimensions

Readers on

mendeley
82 Mendeley
Title
Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry
Published in
International Journal of Nanomedicine, January 2017
DOI 10.2147/ijn.s123236
Pubmed ID
Authors

Adrian-Claudiu Popa, George Stan, Marius-Adrian Husanu, Ionel Mercioniu, Luis Santos, Hugo Fernandes, Jose Ferreira

Abstract

Synthetic physiological fluids are currently used as a first in vitro bioactivity assessment for bone grafts. Our understanding about the interactions taking place at the fluid-implant interface has evolved remarkably during the last decade, and does not comply with the traditional International Organization for Standardization/final draft International Standard 23317 protocol in purely inorganic simulated body fluid. The advances in our knowledge point to the need of a true paradigm shift toward testing physiological fluids with enhanced biomimicry and a better understanding of the materials' structure-dissolution behavior. This will contribute to "upgrade" our vision of entire cascades of events taking place at the implant surfaces upon immersion in the testing media or after implantation. Starting from an osteoinductive bioglass composition with the ability to alleviate the oxidative stress, thin bioglass films with different degrees of polymerization were deposited onto titanium substrates. Their biomineralization activity in simulated body fluid and in a series of new inorganic-organic media with increasing biomimicry that more closely simulated the human intercellular environment was compared. A comprehensive range of advanced characterization tools (scanning electron microscopy; grazing-incidence X-ray diffraction; Fourier-transform infrared, micro-Raman, energy-dispersive, X-ray photoelectron, and surface-enhanced laser desorption/ionization time-of-flight mass spectroscopies; and cytocompatibility assays using mesenchymal stem cells) were used. The information gathered is very useful to biologists, biophysicists, clinicians, and material scientists with special interest in teaching and research. By combining all the analyses, we propose herein a step forward toward establishing an improved unified protocol for testing the bioactivity of implant materials.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 81 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 22%
Student > Master 14 17%
Researcher 12 15%
Student > Bachelor 10 12%
Student > Doctoral Student 3 4%
Other 9 11%
Unknown 16 20%
Readers by discipline Count As %
Engineering 15 18%
Materials Science 14 17%
Biochemistry, Genetics and Molecular Biology 6 7%
Chemistry 6 7%
Medicine and Dentistry 6 7%
Other 10 12%
Unknown 25 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2017.
All research outputs
#3,905,408
of 9,087,585 outputs
Outputs from International Journal of Nanomedicine
#332
of 1,982 outputs
Outputs of similar age
#126,123
of 311,722 outputs
Outputs of similar age from International Journal of Nanomedicine
#15
of 85 outputs
Altmetric has tracked 9,087,585 research outputs across all sources so far. This one has received more attention than most of these and is in the 56th percentile.
So far Altmetric has tracked 1,982 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,722 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.