Title |
Racial differences in the association of CD14 polymorphisms with serum total IgE levels and allergen skin test reactivity
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Published in |
Journal of Asthma and Allergy, June 2013
|
DOI | 10.2147/jaa.s42695 |
Pubmed ID | |
Authors |
ZongYao Wang, John S Sundy, Catherine M Foss, Huiman X Barnhart, Scott M Palmer, Sallie D Allgood, Evan Trudeau, Katie M Alexander, Marc C Levesque |
Abstract |
The CD14 C-159T single nucleotide polymorphism (SNP) has been investigated widely as a candidate genetic locus in patients with allergic disease. There are conflicting results for the association of the CD14 C-159T SNP with total serum immunoglobulin E (IgE) levels and atopy. There are limited data regarding the association of the CD14 C-159T SNP in subjects of African ancestry. The aim of the study was to determine whether the C-159T SNP and other CD14 SNPs (C1188G, C1341T) were associated with total serum IgE levels and with allergy skin test results in nonatopic and atopic subjects; as well as in Caucasian and African American subjects. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 33% |
Student > Postgraduate | 2 | 22% |
Student > Bachelor | 1 | 11% |
Researcher | 1 | 11% |
Unknown | 2 | 22% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 1 | 11% |
Unknown | 3 | 33% |