| Title |
Efficacy of a short cognitive training program in patients with multiple sclerosis
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, February 2017
|
| DOI | 10.2147/ndt.s124448 |
| Pubmed ID | |
| Authors |
María Yaiza Pérez-Martín, Montserrat González-Platas, Pablo Eguía-del Río, Cristina Croissier-Elías, Alejandro Jiménez Sosa |
| Abstract |
Cognitive impairment is a common feature in multiple sclerosis (MS) and may have a substantial impact on quality of life. Evidence about the effectiveness of neuropsychological rehabilitation is still limited, but current data suggest that computer-assisted cognitive training improves cognitive performance. The objective of this study was to evaluate the efficacy of combined computer-assisted training supported by home-based neuropsychological training to improve attention, processing speed, memory and executive functions during 3 consecutive months. In this randomized controlled study blinded for the evaluators, 62 MS patients with clinically stable disease and mild-to-moderate levels of cognitive impairment were randomized to receive a computer-assisted neuropsychological training program (n=30) or no intervention (control group [CG]; n=32). The cognitive assessment included the Brief Repeatable Battery of Neuropsychological Test. Other secondary measures included subjective cognitive impairment, anxiety and depression, fatigue and quality of life measures. The treatment group (TG) showed significant improvements in measures of verbal memory, working memory and phonetic fluency after intervention, and repeated measures analysis of covariance revealed a positive effect in most of the functions. The control group (CG) did not show changes. The TG showed a significant reduction in anxiety symptoms and significant improvement in quality of life. There were no improvements in fatigue levels and depressive symptoms. Cognitive intervention with a computer-assisted training supported by home training between face-to-face sessions is a useful tool to treat patients with MS and improve functions such as verbal memory, working memory and phonetic fluency. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | <1% |
| Unknown | 170 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 31 | 18% |
| Student > Bachelor | 23 | 13% |
| Researcher | 19 | 11% |
| Student > Ph. D. Student | 19 | 11% |
| Student > Doctoral Student | 10 | 6% |
| Other | 33 | 19% |
| Unknown | 36 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 46 | 27% |
| Medicine and Dentistry | 22 | 13% |
| Neuroscience | 20 | 12% |
| Nursing and Health Professions | 11 | 6% |
| Agricultural and Biological Sciences | 5 | 3% |
| Other | 21 | 12% |
| Unknown | 46 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2017.
All research outputs
#16,725,651
of 25,382,440 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,719
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Outputs of similar age
#256,839
of 424,972 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#47
of 74 outputs
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