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Abnormal resting-state brain activities in patients with first-episode obsessive-compulsive disorder

Overview of attention for article published in Neuropsychiatric Disease and Treatment, February 2017
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Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

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23 Dimensions

Readers on

mendeley
24 Mendeley
Title
Abnormal resting-state brain activities in patients with first-episode obsessive-compulsive disorder
Published in
Neuropsychiatric Disease and Treatment, February 2017
DOI 10.2147/ndt.s117510
Pubmed ID
Authors

Qihui Niu, Lei Yang, Xueqin Song, Congying Chu, Hao Liu, Lifang Zhang, Yan Li, Xiang Zhang, Jingliang Cheng, Youhui Li

Abstract

This paper attempts to explore the brain activity of patients with obsessive-compulsive disorder (OCD) and its correlation with the disease at resting duration in patients with first-episode OCD, providing a forceful imaging basis for clinic diagnosis and pathogenesis of OCD. Twenty-six patients with first-episode OCD and 25 healthy controls (HC group; matched for age, sex, and education level) underwent functional magnetic resonance imaging (fMRI) scanning at resting state. Statistical parametric mapping 8, data processing assistant for resting-state fMRI analysis toolkit, and resting state fMRI data analysis toolkit packages were used to process the fMRI data on Matlab 2012a platform, and the difference of regional homogeneity (ReHo) values between the OCD group and HC group was detected with independent two-sample t-test. With age as a concomitant variable, the Pearson correlation analysis was adopted to study the correlation between the disease duration and ReHo value of whole brain. Compared with HC group, the ReHo values in OCD group were decreased in brain regions, including left thalamus, right thalamus, right paracentral lobule, right postcentral gyrus, and the ReHo value was increased in the left angular gyrus region. There was a negative correlation between disease duration and ReHo value in the bilateral orbitofrontal cortex (OFC). OCD is a multifactorial disease generally caused by abnormal activities of many brain regions at resting state. Worse brain activity of the OFC is related to the OCD duration, which provides a new insight to the pathogenesis of OCD.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 21%
Student > Doctoral Student 2 8%
Professor 2 8%
Researcher 2 8%
Student > Postgraduate 2 8%
Other 4 17%
Unknown 7 29%
Readers by discipline Count As %
Psychology 8 33%
Medicine and Dentistry 4 17%
Neuroscience 2 8%
Social Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 0 0%
Unknown 8 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2017.
All research outputs
#9,887,728
of 16,109,166 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,311
of 2,584 outputs
Outputs of similar age
#146,329
of 262,630 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#43
of 71 outputs
Altmetric has tracked 16,109,166 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,584 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,630 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.