| Title |
Language impairment in Alzheimer's disease and benefits of acetylcholinesterase inhibitors
|
|---|---|
| Published in |
Clinical Interventions in Aging, August 2013
|
| DOI | 10.2147/cia.s39959 |
| Pubmed ID | |
| Authors |
Steven H Ferris, Martin Farlow |
| Abstract |
Alzheimer's disease is characterized by progressively worsening deficits in several cognitive domains, including language. Language impairment in Alzheimer's disease primarily occurs because of decline in semantic and pragmatic levels of language processing. Given the centrality of language to cognitive function, a number of language-specific scales have been developed to assess language deficits throughout progression of the disease and to evaluate the effects of pharmacotherapy on language function. Trials of acetylcholinesterase inhibitors, used for the treatment of clinical symptoms of Alzheimer's disease, have generally focused on overall cognitive effects. However, in the current report, we review data indicating specific beneficial effects of acetylcholinesterase inhibitors on language abilities in patients with Alzheimer's disease, with a particular focus on outcomes among patients in the moderate and severe disease stages, during which communication is at risk and preservation is particularly important. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 40% |
| Practitioners (doctors, other healthcare professionals) | 2 | 40% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 256 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 251 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 47 | 18% |
| Student > Ph. D. Student | 32 | 13% |
| Student > Master | 24 | 9% |
| Researcher | 22 | 9% |
| Student > Doctoral Student | 16 | 6% |
| Other | 45 | 18% |
| Unknown | 70 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 38 | 15% |
| Medicine and Dentistry | 35 | 14% |
| Nursing and Health Professions | 18 | 7% |
| Neuroscience | 18 | 7% |
| Linguistics | 13 | 5% |
| Other | 53 | 21% |
| Unknown | 81 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2024.
All research outputs
#1,420,388
of 25,732,188 outputs
Outputs from Clinical Interventions in Aging
#148
of 1,979 outputs
Outputs of similar age
#11,902
of 210,961 outputs
Outputs of similar age from Clinical Interventions in Aging
#4
of 56 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,979 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,961 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.