Title |
Helicobacter pylori infection is not associated with failure to thrive: a case–control study
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Published in |
Therapeutics and Clinical Risk Management, February 2017
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DOI | 10.2147/tcrm.s123148 |
Pubmed ID | |
Authors |
Nan-Chang Chiu, Chien-Yu Lin, Hsin Chi, Chun-Yan Yeung, Wei-Hsin Ting, Wai-Tao Chan, Chuen-Bin Jiang, Sung-Tse Li, Chao-Hsu Lin, Hung-Chang Lee |
Abstract |
The long-term impact of Helicobacter pylori infection is complex, and concerns about the need for eradication exist. We conducted this case control study to investigate the association between H. pylori infection and failure to thrive (FTT). From January 2009 to December 2011, 53 children with FTT group and matched children with the same sex and age and similar socioeconomic status without FTT (control group) were enrolled. A questionnaire was administered to the parents/guardian, and a (13)C-urea breath test was performed to detect H. pylori infection. We found that the total prevalence of H. pylori infection was 29.2% and that there was no association between FTT and H. pylori infection (FTT group: 32%; control group: 26.4%; P=0.67). Short stature was more common in the FTT group and abdominal pain in the control group (FTT group: 37.7%; control group: 11.3%; P=0.003). In a comparison between the H. pylori-positive and -negative groups, abdominal pain (87.1% vs 64%; P=0.032) and the frequency of endoscopy (74.2% vs 32%; P<0.001) were significantly more common in the H. pylori-positive group. We found that children with H. pylori infection are at an increased risk for abdominal pain and that FTT is not associated with H. pylori infection. The decision for eradication should be evaluated carefully and individualized. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 22% |
Librarian | 2 | 11% |
Student > Ph. D. Student | 2 | 11% |
Professor | 2 | 11% |
Other | 1 | 6% |
Other | 3 | 17% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 28% |
Immunology and Microbiology | 2 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Nursing and Health Professions | 1 | 6% |
Unspecified | 1 | 6% |
Other | 3 | 17% |
Unknown | 5 | 28% |