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Postpartum depression: psychoneuroimmunological underpinnings and treatment

Overview of attention for article published in Neuropsychiatric Disease and Treatment, February 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
3 news outlets
twitter
1 X user

Citations

dimensions_citation
62 Dimensions

Readers on

mendeley
180 Mendeley
Title
Postpartum depression: psychoneuroimmunological underpinnings and treatment
Published in
Neuropsychiatric Disease and Treatment, February 2013
DOI 10.2147/ndt.s25320
Pubmed ID
Authors

George Anderson, Michael Maes

Abstract

Postpartum depression (PPD) is common, occurring in 10%-15% of women. Due to concerns about teratogenicity of medications in the suckling infant, the treatment of PPD has often been restricted to psychotherapy. We review here the biological underpinnings to PPD, suggesting a powerful role for the tryptophan catabolites, indoleamine 2,3-dixoygenase, serotonin, and autoimmunity in mediating the consequences of immuno-inflammation and oxidative and nitrosative stress. It is suggested that the increased inflammatory potential, the decreases in endogenous anti-inflammatory compounds together with decreased omega-3 poly-unsaturated fatty acids, in the postnatal period cause an inflammatory environment. The latter may result in the utilization of peripheral inflammatory products, especially kynurenine, in driving the central processes producing postnatal depression. The pharmacological treatment of PPD is placed in this context, and recommendations for more refined and safer treatments are made, including the better utilization of the antidepressant, and the anti-inflammatory and antioxidant effects of melatonin.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Spain 2 1%
United States 1 <1%
Uruguay 1 <1%
Unknown 174 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 28 16%
Student > Bachelor 25 14%
Student > Ph. D. Student 21 12%
Student > Doctoral Student 14 8%
Researcher 13 7%
Other 42 23%
Unknown 37 21%
Readers by discipline Count As %
Medicine and Dentistry 42 23%
Psychology 26 14%
Biochemistry, Genetics and Molecular Biology 13 7%
Neuroscience 13 7%
Nursing and Health Professions 12 7%
Other 29 16%
Unknown 45 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 26. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2020.
All research outputs
#1,474,644
of 25,374,917 outputs
Outputs from Neuropsychiatric Disease and Treatment
#194
of 3,132 outputs
Outputs of similar age
#13,382
of 291,228 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#2
of 43 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,228 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.