| Title |
Alagille syndrome: clinical perspectives
|
|---|---|
| Published in |
The Application of Clinical Genetics, June 2016
|
| DOI | 10.2147/tacg.s86420 |
| Pubmed ID | |
| Authors |
Maha Saleh, Binita M Kamath, David Chitayat |
| Abstract |
Alagille syndrome is an autosomal dominant, complex multisystem disorder characterized by the presence of three out of five major clinical criteria: cholestasis with bile duct paucity on liver biopsy, congenital cardiac defects (with particular involvement of the pulmonary arteries), posterior embryotoxon in the eye, characteristic facial features, and butterfly vertebrae. Renal and vascular abnormalities can also occur. Inter- and intrafamilial variabilities in the clinical manifestations are common. We reviewed the clinical features and management as well as the molecular basis of Alagille syndrome. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 149 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 22 | 15% |
| Researcher | 13 | 9% |
| Other | 11 | 7% |
| Student > Doctoral Student | 10 | 7% |
| Student > Master | 10 | 7% |
| Other | 24 | 16% |
| Unknown | 59 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 50 | 34% |
| Biochemistry, Genetics and Molecular Biology | 15 | 10% |
| Agricultural and Biological Sciences | 5 | 3% |
| Nursing and Health Professions | 4 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 6 | 4% |
| Unknown | 66 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2018.
All research outputs
#8,580,937
of 25,748,735 outputs
Outputs from The Application of Clinical Genetics
#1
of 1 outputs
Outputs of similar age
#128,145
of 354,808 outputs
Outputs of similar age from The Application of Clinical Genetics
#1
of 1 outputs
Altmetric has tracked 25,748,735 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 1 research outputs from this source. They receive a mean Attention Score of 3.2. This one scored the same or higher as 0 of them.
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We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them