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Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium

Overview of attention for article published in International Journal of Nanomedicine, September 2013
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1 tweeter

Citations

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Readers on

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25 Mendeley
Title
Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium
Published in
International Journal of Nanomedicine, September 2013
DOI 10.2147/ijn.s49323
Pubmed ID
Authors

Hamdi Trabelsi, Iness Azzouz, Ferchichi, Tebourbi, Mohsen Sakly, Hafedh Abdelmelek

Abstract

The aim of this study was to investigate the interaction of cadmium chloride with mineral elements in rat nephrocytes in terms of the biosynthesis of nanocomplexes. The results show that selenium supplementation enhanced cadmium accumulation in kidneys. Analysis of the fluorescence revealed an increase in red fluorescence in the kidneys of rats co-exposed to cadmium and selenium. Interestingly, X-ray diffraction measurements carried out on kidney fractions of co-exposed rats point to the biosynthesis of cadmium selenide and/or sulfide nanoparticles (about 62 nm in size). Oxidative stress assays showed the ability of selenium to reduce lipid peroxidation and to restore glutathione peroxidase and superoxide dismutase activity in kidneys. Hence, cadmium complexation with selenium and sulfur at a nanoscale level could reduce oxidative stress induced by cadmium in kidneys.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 20%
Student > Bachelor 3 12%
Student > Master 3 12%
Researcher 2 8%
Professor 1 4%
Other 3 12%
Unknown 8 32%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 12%
Biochemistry, Genetics and Molecular Biology 3 12%
Chemistry 3 12%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Chemical Engineering 1 4%
Other 4 16%
Unknown 9 36%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2014.
All research outputs
#15,281,593
of 22,725,280 outputs
Outputs from International Journal of Nanomedicine
#2,227
of 3,800 outputs
Outputs of similar age
#123,886
of 200,191 outputs
Outputs of similar age from International Journal of Nanomedicine
#79
of 104 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,800 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,191 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.