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The drug efficacy and adverse reactions in a mouse model of oral squamous cell carcinoma treated with oxaliplatin at different time points during a day

Overview of attention for article published in Drug Design, Development and Therapy, June 2013
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1 tweeter

Citations

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5 Dimensions

Readers on

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19 Mendeley
Title
The drug efficacy and adverse reactions in a mouse model of oral squamous cell carcinoma treated with oxaliplatin at different time points during a day
Published in
Drug Design, Development and Therapy, June 2013
DOI 10.2147/dddt.s46323
Pubmed ID
Authors

Kai Yang, Ningbo Zhao, Zhao, Dan Chen, Yadong Li

Abstract

Recent studies have shown that the growth and proliferation of cancer cells in vivo exhibit circadian rhythm, and the efficacy and adverse reactions of platinum-based anticancer drugs administered at different times of the day vary significantly on colon cancer. However, since the circadian rhythms of growth and proliferation of various cancer cells often differ, the question of whether the administration of platinum anticancer drugs at different times of the day exerts significantly different efficacy and adverse effects on oral cancers remains to be elucidated. This study has compared the efficacy and adverse effects of oxaliplatin (L-OHP) administration at different times during a day on oral squamous cell carcinoma in mice and has analyzed cellular circadian rhythms.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 5%
France 1 5%
Unknown 17 89%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 32%
Student > Ph. D. Student 3 16%
Student > Postgraduate 2 11%
Librarian 2 11%
Professor 2 11%
Other 3 16%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 9 47%
Agricultural and Biological Sciences 2 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Nursing and Health Professions 1 5%
Psychology 1 5%
Other 2 11%
Unknown 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2013.
All research outputs
#3,563,022
of 4,507,509 outputs
Outputs from Drug Design, Development and Therapy
#394
of 566 outputs
Outputs of similar age
#80,587
of 101,300 outputs
Outputs of similar age from Drug Design, Development and Therapy
#25
of 35 outputs
Altmetric has tracked 4,507,509 research outputs across all sources so far. This one is in the 3rd percentile – i.e., 3% of other outputs scored the same or lower than it.
So far Altmetric has tracked 566 research outputs from this source. They receive a mean Attention Score of 1.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 101,300 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.