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Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

Overview of attention for article published in Therapeutics and Clinical Risk Management, July 2013
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Title
Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers
Published in
Therapeutics and Clinical Risk Management, July 2013
DOI 10.2147/tcrm.s39024
Pubmed ID
Authors

Mario Del Tacca, Giuseppe Pasqualetti, Giovanni Gori, Pasquale Pepe, Antonello Di Paolo, Marianna Lastella, Ferdinando De Negri, Corrado Blandizzi

Abstract

The primary aim of the present study was to assess the pharmacokinetic bioequivalence between a generic formulation of meloxicam 15 mg tablets (Meloxicam Hexal) and its respective brand product (Mobic), in order to verify whether the generic product conforms to the regulatory standards of bioequivalence in the postmarketing setting. As a secondary exploratory aim, the pharmacodynamic effects of the two formulations were also evaluated by means of rating scales following hyperalgesia induced by cutaneous freeze injury.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 18%
Researcher 6 18%
Student > Bachelor 5 15%
Student > Doctoral Student 4 12%
Other 4 12%
Other 6 18%
Unknown 3 9%
Readers by discipline Count As %
Medicine and Dentistry 12 35%
Pharmacology, Toxicology and Pharmaceutical Science 7 21%
Agricultural and Biological Sciences 5 15%
Immunology and Microbiology 1 3%
Social Sciences 1 3%
Other 3 9%
Unknown 5 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2013.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Therapeutics and Clinical Risk Management
#926
of 1,323 outputs
Outputs of similar age
#130,885
of 206,704 outputs
Outputs of similar age from Therapeutics and Clinical Risk Management
#7
of 9 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,323 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,704 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.