Title |
Intraoperative radiation therapy for breast cancer patients: current perspectives
|
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Published in |
Breast cancer targets and therapy, April 2017
|
DOI | 10.2147/bctt.s112516 |
Pubmed ID | |
Authors |
Sunil W Dutta, Shayna L Showalter, Timothy N Showalter, Bruce Libby, Daniel M Trifiletti |
Abstract |
Accelerated partial breast irradiation (APBI) provides an attractive alternative to whole breast irradiation (WBI) through normal tissue radiation exposure and reduced treatment duration. Intraoperative radiation therapy (IORT) is a form of APBI with the shortest time interval, as it delivers the entirety of a planned radiation course at the time of breast surgery. However, faster is not always better, and IORT has been met with healthy skepticism. Patients treated with IORT have an increased compliance and overall satisfaction when compared to patients treated with WBI. However, early randomized trial results demonstrated an increased rate of recurrence after IORT, slowing its widespread adoption. Despite these controversies, IORT utilization is increasing nationally and several novel developments are aimed at continuing to minimize the risk of recurrence and treatment-related toxicity while maximizing the patient experience. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 65 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 15% |
Other | 9 | 14% |
Researcher | 7 | 11% |
Student > Master | 5 | 8% |
Student > Doctoral Student | 4 | 6% |
Other | 12 | 18% |
Unknown | 18 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 25% |
Nursing and Health Professions | 7 | 11% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Physics and Astronomy | 4 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 10 | 15% |
Unknown | 22 | 34% |