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Photoprotective effects of apple peel nanoparticles

Overview of attention for article published in International Journal of Nanomedicine, December 2013
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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Readers on

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55 Mendeley
Title
Photoprotective effects of apple peel nanoparticles
Published in
International Journal of Nanomedicine, December 2013
DOI 10.2147/ijn.s54048
Pubmed ID
Authors

Devasier Bennet, Chan Kang, Jongback Gang, Sanghyo Kim

Abstract

Plants contain enriched bioactive molecules that can protect against skin diseases. Bioactive molecules become unstable and ineffective due to unfavorable conditions. In the present study, to improve the therapeutic efficacy of phytodrugs and enhance photoprotective capability, we used poly(D,L-lactide-co-glycolide) as a carrier of apple peel ethanolic extract (APETE) on permeation-enhanced nanoparticles (nano-APETE). The in vitro toxicity of nano-APETE-treated dermal fibroblast cells were studied in a bioimpedance system, and the results coincided with the viability assay. In addition, the continuous real-time evaluations of photodamage and photoprotective effect of nano-APETE on cells were studied. Among three different preparations of nano-APETE, the lowest concentration provided small, spherical, monodispersed, uniform particles which show high encapsulation, enhanced uptake, effective scavenging, and sustained intracellular delivery. Also, the nano-APETE is more flexible, allowing it to permeate through skin lipid membrane and release the drug in a sustained manner, thus confirming its ability as a sustained transdermal delivery. In summary, 50 μM nano-APETE shows strong synergistic photoprotective effects, thus demonstrating its higher activity on target sites for the treatment of skin damage, and would be of broad interest in the field of skin therapeutics.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 18%
Other 6 11%
Researcher 6 11%
Student > Master 6 11%
Student > Bachelor 5 9%
Other 11 20%
Unknown 11 20%
Readers by discipline Count As %
Chemistry 10 18%
Agricultural and Biological Sciences 6 11%
Chemical Engineering 5 9%
Engineering 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Other 8 15%
Unknown 17 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2014.
All research outputs
#16,188,873
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#1,880
of 4,077 outputs
Outputs of similar age
#190,762
of 321,951 outputs
Outputs of similar age from International Journal of Nanomedicine
#45
of 100 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,951 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.