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Photoprotective effects of apple peel nanoparticles

Overview of attention for article published in International Journal of Nanomedicine, December 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 tweeters

Citations

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12 Dimensions

Readers on

mendeley
33 Mendeley
Title
Photoprotective effects of apple peel nanoparticles
Published in
International Journal of Nanomedicine, December 2013
DOI 10.2147/ijn.s54048
Pubmed ID
Authors

Sanghyo Kim, Devasier Bennet, Se Chan Kang, Jongback Gang

Abstract

Plants contain enriched bioactive molecules that can protect against skin diseases. Bioactive molecules become unstable and ineffective due to unfavorable conditions. In the present study, to improve the therapeutic efficacy of phytodrugs and enhance photoprotective capability, we used poly(D,L-lactide-co-glycolide) as a carrier of apple peel ethanolic extract (APETE) on permeation-enhanced nanoparticles (nano-APETE). The in vitro toxicity of nano-APETE-treated dermal fibroblast cells were studied in a bioimpedance system, and the results coincided with the viability assay. In addition, the continuous real-time evaluations of photodamage and photoprotective effect of nano-APETE on cells were studied. Among three different preparations of nano-APETE, the lowest concentration provided small, spherical, monodispersed, uniform particles which show high encapsulation, enhanced uptake, effective scavenging, and sustained intracellular delivery. Also, the nano-APETE is more flexible, allowing it to permeate through skin lipid membrane and release the drug in a sustained manner, thus confirming its ability as a sustained transdermal delivery. In summary, 50 μM nano-APETE shows strong synergistic photoprotective effects, thus demonstrating its higher activity on target sites for the treatment of skin damage, and would be of broad interest in the field of skin therapeutics.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 27%
Researcher 5 15%
Student > Master 4 12%
Other 3 9%
Professor 3 9%
Other 7 21%
Unknown 2 6%
Readers by discipline Count As %
Chemistry 9 27%
Agricultural and Biological Sciences 6 18%
Engineering 5 15%
Chemical Engineering 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 5 15%
Unknown 4 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2014.
All research outputs
#2,124,971
of 4,507,509 outputs
Outputs from International Journal of Nanomedicine
#373
of 1,146 outputs
Outputs of similar age
#52,553
of 122,659 outputs
Outputs of similar age from International Journal of Nanomedicine
#46
of 125 outputs
Altmetric has tracked 4,507,509 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,146 research outputs from this source. They receive a mean Attention Score of 1.7. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,659 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.