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Near-infrared quantum dots for HER2 localization and imaging of cancer cells

Overview of attention for article published in International Journal of Nanomedicine, March 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

twitter
5 tweeters

Citations

dimensions_citation
49 Dimensions

Readers on

mendeley
68 Mendeley
Title
Near-infrared quantum dots for HER2 localization and imaging of cancer cells
Published in
International Journal of Nanomedicine, March 2014
DOI 10.2147/ijn.s51535
Pubmed ID
Authors

Alexander Seifalian, Sarwat Rizvi, Sepideh Rouhi, Shohei Taniguchi, Shi Yu Yang, Mark Green, Mo Keshtgar

Abstract

Quantum dots are fluorescent nanoparticles with unique photophysical properties that allow them to be used as diagnostic, therapeutic, and theranostic agents, particularly in medical and surgical oncology. Near-infrared-emitting quantum dots can be visualized in deep tissues because the biological window is transparent to these wavelengths. Their small sizes and free surface reactive groups that can be conjugated to biomolecules make them ideal probes for in vivo cancer localization, targeted chemotherapy, and image-guided cancer surgery. The human epidermal growth factor receptor 2 gene (HER2/neu) is overexpressed in 25%-30% of breast cancers. The current methods of detection for HER2 status, including immunohistochemistry and fluorescence in situ hybridization, are used ex vivo and cannot be used in vivo. In this paper, we demonstrate the application of near-infrared-emitting quantum dots for HER2 localization in fixed and live cancer cells as a first step prior to their in vivo application.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Poland 1 1%
Denmark 1 1%
Unknown 64 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 25%
Researcher 11 16%
Student > Master 11 16%
Student > Bachelor 9 13%
Student > Postgraduate 4 6%
Other 9 13%
Unknown 7 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 18%
Biochemistry, Genetics and Molecular Biology 12 18%
Medicine and Dentistry 10 15%
Chemistry 8 12%
Materials Science 4 6%
Other 12 18%
Unknown 10 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2016.
All research outputs
#6,463,566
of 12,438,331 outputs
Outputs from International Journal of Nanomedicine
#622
of 2,456 outputs
Outputs of similar age
#67,993
of 190,729 outputs
Outputs of similar age from International Journal of Nanomedicine
#31
of 103 outputs
Altmetric has tracked 12,438,331 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,456 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,729 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.