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Dove Medical Press

Near-infrared quantum dots for HER2 localization and imaging of cancer cells

Overview of attention for article published in International Journal of Nanomedicine, March 2014
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  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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85 Mendeley
Title
Near-infrared quantum dots for HER2 localization and imaging of cancer cells
Published in
International Journal of Nanomedicine, March 2014
DOI 10.2147/ijn.s51535
Pubmed ID
Authors

Sarwat B Rizvi, Sepideh Rouhi, Shohei Taniguchi, Shi Yu Yang, Mark Green, Mo Keshtgar, Alexander M Seifalian

Abstract

Quantum dots are fluorescent nanoparticles with unique photophysical properties that allow them to be used as diagnostic, therapeutic, and theranostic agents, particularly in medical and surgical oncology. Near-infrared-emitting quantum dots can be visualized in deep tissues because the biological window is transparent to these wavelengths. Their small sizes and free surface reactive groups that can be conjugated to biomolecules make them ideal probes for in vivo cancer localization, targeted chemotherapy, and image-guided cancer surgery. The human epidermal growth factor receptor 2 gene (HER2/neu) is overexpressed in 25%-30% of breast cancers. The current methods of detection for HER2 status, including immunohistochemistry and fluorescence in situ hybridization, are used ex vivo and cannot be used in vivo. In this paper, we demonstrate the application of near-infrared-emitting quantum dots for HER2 localization in fixed and live cancer cells as a first step prior to their in vivo application.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Poland 1 1%
Denmark 1 1%
Unknown 81 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 19%
Researcher 15 18%
Student > Master 12 14%
Student > Bachelor 10 12%
Student > Doctoral Student 5 6%
Other 13 15%
Unknown 14 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 15%
Medicine and Dentistry 12 14%
Agricultural and Biological Sciences 11 13%
Chemistry 11 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Other 16 19%
Unknown 17 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2016.
All research outputs
#14,599,900
of 25,373,627 outputs
Outputs from International Journal of Nanomedicine
#1,525
of 4,123 outputs
Outputs of similar age
#115,644
of 236,365 outputs
Outputs of similar age from International Journal of Nanomedicine
#31
of 105 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,123 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,365 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.