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The new concepts on overcoming drug resistance in lung cancer

Overview of attention for article published in Drug Design, Development and Therapy, June 2014
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Mentioned by

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1 tweeter

Citations

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23 Dimensions

Readers on

mendeley
32 Mendeley
Title
The new concepts on overcoming drug resistance in lung cancer
Published in
Drug Design, Development and Therapy, June 2014
DOI 10.2147/dddt.s60672
Pubmed ID
Authors

Xifeng Dong, Cuiping Xu, Ping Lei, Weisan Zhang

Abstract

Lung cancer is one of the most deadly diseases worldwide. The current first-line therapies include chemotherapy using epidermal growth factor receptor tyrosine kinase inhibitors and radiotherapies. With the current progress in identifying new molecular targets, acquired drug resistance stands as an obstacle for good prognosis. About half the patients receiving epidermal growth factor receptor-tyrosine kinase inhibitor treatments develop resistance. Although extensive studies have been applied to elucidate the underlying mechanisms, evidence is far from enough to establish a well-defined picture to correct resistance. In the review, we will discuss four different currently developed strategies that have the potential to overcome drug resistance in lung cancer therapies and facilitate prolonged anticancer effects of the first-line therapies.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Austria 1 3%
Canada 1 3%
Unknown 29 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Student > Bachelor 6 19%
Student > Postgraduate 4 13%
Researcher 4 13%
Other 2 6%
Other 6 19%
Unknown 4 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 31%
Agricultural and Biological Sciences 6 19%
Pharmacology, Toxicology and Pharmaceutical Science 5 16%
Medicine and Dentistry 5 16%
Immunology and Microbiology 1 3%
Other 1 3%
Unknown 4 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2014.
All research outputs
#10,012,012
of 12,510,237 outputs
Outputs from Drug Design, Development and Therapy
#764
of 1,315 outputs
Outputs of similar age
#125,952
of 188,523 outputs
Outputs of similar age from Drug Design, Development and Therapy
#21
of 29 outputs
Altmetric has tracked 12,510,237 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,315 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,523 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.