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Low uric acid is a risk factor in mild cognitive impairment

Overview of attention for article published in Neuropsychiatric Disease and Treatment, September 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

twitter
7 tweeters
facebook
2 Facebook pages

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
26 Mendeley
Title
Low uric acid is a risk factor in mild cognitive impairment
Published in
Neuropsychiatric Disease and Treatment, September 2017
DOI 10.2147/ndt.s145812
Pubmed ID
Authors

LingLing Xue, YongBing Liu, HuiPing Xue, Jin Xue, KaiXuan Sun, LinFeng Wu, Ping Hou

Abstract

Mild cognitive impairment (MCI) represents a transitional stage between normal aging and dementia. Uric acid is a water-soluble antioxidant found in the body. Many recent studies have found that uric acid plays an important role in cognitive impairment, although the effects of uric acid on MCI are not clear. The objective of this study was to explore the relationship between uric acid and MCI. Using a random sampling method, this study investigated 58 patients with MCI and 57 healthy elderly from January 2016 to November 2016. Demographic information was collected, the subjects were evaluated using the Mini Mental Status Examination (MMSE), and uric acid was measured in fasting venous blood. A total of 57 (49.6%) participants are healthy and 58 (50.4%) participants had MCI. The uric acid level was significantly lower in the patients with MCI (292.28±63.71 μmol/L) than in the normal controls (322.49±78.70 μmol/L; P<0.05). There were significant positive correlations between the MMSE scores, for each dimension and the total score, and uric acid level (all P<0.05). Multivariate logistic regression models illustrated that uric acid was a protective factor for MCI (odds ratio =0.999, 95% CI =0.987-0.999). A low uric acid level is a risk factor for MCI, and an appropriate increase in uric acid can be used to slow down the occurrence and development of MCI.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 12%
Student > Master 3 12%
Student > Ph. D. Student 2 8%
Lecturer 1 4%
Student > Doctoral Student 1 4%
Other 5 19%
Unknown 11 42%
Readers by discipline Count As %
Medicine and Dentistry 4 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Nursing and Health Professions 2 8%
Psychology 2 8%
Immunology and Microbiology 1 4%
Other 4 15%
Unknown 11 42%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2017.
All research outputs
#3,428,690
of 15,002,747 outputs
Outputs from Neuropsychiatric Disease and Treatment
#440
of 2,466 outputs
Outputs of similar age
#70,183
of 271,921 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#11
of 78 outputs
Altmetric has tracked 15,002,747 research outputs across all sources so far. Compared to these this one has done well and is in the 77th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,466 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,921 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.