Title |
Lower extremity amputation in peripheral artery disease: improving patient outcomes
|
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Published in |
Vascular Health and Risk Management, July 2014
|
DOI | 10.2147/vhrm.s50588 |
Pubmed ID | |
Authors |
Aparna Swaminathan, Sreekanth Vemulapalli, Manesh R Patel, W Schuyler Jones |
Abstract |
Peripheral artery disease affects over eight million Americans and is associated with an increased risk of mortality, cardiovascular disease, functional limitation, and limb loss. In its most severe form, critical limb ischemia, patients are often treated with lower extremity (LE) amputation (LEA), although the overall incidence of LEA is declining. In the US, there is significant geographic variation in the performing of major LEA. The rate of death after major LEA in the US is approximately 48% at 1 year and 71% at 3 years. Despite this significant morbidity and mortality, the use of diagnostic testing (both noninvasive and invasive testing) in the year prior to LEA is low and varies based on patient, provider, and regional factors. In this review we discuss the significance of LEA and methods to reduce its occurrence. These methods include improved recognition of the risk factors for LEA by clinicians and patients, strong advocacy for noninvasive and/or invasive imaging prior to LEA, improved endovascular revascularization techniques, and novel therapies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Romania | 1 | <1% |
Unknown | 156 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 28 | 18% |
Student > Master | 22 | 14% |
Other | 19 | 12% |
Researcher | 12 | 8% |
Student > Postgraduate | 12 | 8% |
Other | 23 | 15% |
Unknown | 42 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 64 | 41% |
Nursing and Health Professions | 12 | 8% |
Engineering | 10 | 6% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Chemistry | 3 | 2% |
Other | 14 | 9% |
Unknown | 49 | 31% |