↓ Skip to main content

Dove Medical Press

Article Metrics

Off-label use of hormones as an antiaging strategy: a review

Overview of attention for article published in Clinical Interventions in Aging, July 2014
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#36 of 1,374)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
4 news outlets
twitter
3 tweeters
facebook
1 Facebook page
wikipedia
1 Wikipedia page
reddit
1 Redditor

Citations

dimensions_citation
35 Dimensions

Readers on

mendeley
122 Mendeley
Title
Off-label use of hormones as an antiaging strategy: a review
Published in
Clinical Interventions in Aging, July 2014
DOI 10.2147/cia.s48918
Pubmed ID
Authors

Samaras N, Papadopoulou MA, Samaras D, Ongaro F, Nikolaos Samaras, Maria-Aikaterini Papadopoulou, Dimitrios Samaras, Filippo Ongaro

Abstract

Given demographic evolution of the population in modern societies, one of the most important health care needs is successful aging with less frailty and dependency. During the last 20 years, a multitude of anti-aging practices have appeared worldwide, aiming at retarding or even stopping and reversing the effects of aging on the human body. One of the cornerstones of anti-aging is hormone replacement. At present, women live one third of their lives in a state of sex-hormone deficiency. Men are also subject to age-related testosterone decline, but andropause remains frequently under-diagnosed and under-treated. Due to the decline of hormone production from gonads in both sexes, the importance of dehydroepiandrosterone (DHEA) in steroid hormone production increases with age. However, DHEA levels also decrease with age. Also, growth hormone age-associated decrease may be so important that insulin growth factor-1 levels found in elderly individuals are sometimes as low as those encountered in adult patients with established deficiency. Skin aging as well as decreases in lean body mass, bone mineral density, sexual desire and erectile function, intellectual activity and mood have all been related to this decrease of hormone production with age. Great disparities exist between recommendations from scientific societies and actual use of hormone supplements in aging and elderly patients. In this article, we review actual data on the effects of age related hormone decline on the aging process and age-related diseases such as sarcopenia and falls, osteoporosis, cognitive decline, mood disorders, cardiovascular health and sexual activity. We also provide information on the efficiency and safety of hormone replacement protocols in aging patients. Finally, we argue on future perspectives of such protocols as part of everyday practice.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
China 1 <1%
Italy 1 <1%
Iran, Islamic Republic of 1 <1%
Unknown 117 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 19%
Student > Bachelor 17 14%
Student > Ph. D. Student 15 12%
Student > Master 15 12%
Student > Postgraduate 13 11%
Other 39 32%
Readers by discipline Count As %
Medicine and Dentistry 49 40%
Unspecified 18 15%
Agricultural and Biological Sciences 15 12%
Nursing and Health Professions 9 7%
Psychology 5 4%
Other 26 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2019.
All research outputs
#429,683
of 13,457,898 outputs
Outputs from Clinical Interventions in Aging
#36
of 1,374 outputs
Outputs of similar age
#7,561
of 198,898 outputs
Outputs of similar age from Clinical Interventions in Aging
#1
of 12 outputs
Altmetric has tracked 13,457,898 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,374 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,898 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.