Title |
Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease
|
---|---|
Published in |
International Journal of Chronic Obstructive Pulmonary Disease, November 2014
|
DOI | 10.2147/copd.s41476 |
Pubmed ID | |
Authors |
Simon E Brill, Jadwiga A Wedzicha |
Abstract |
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the history of this debilitating lung condition. Associated health care utilization and morbidity are high, and many patients require supplemental oxygen or ventilatory support. The last 2 decades have seen a substantial increase in our understanding of the best way to manage the respiratory failure suffered by many patients during this high-risk period. This review article examines the evidence underlying supplemental oxygen therapy during exacerbations of COPD. We first discuss the epidemiology and pathophysiology of respiratory failure in COPD during exacerbations. The rationale and evidence underlying oxygen therapy, including the risks when administered inappropriately, are then discussed, along with further strategies for ventilatory support. We also review current recommendations for best practice, including methods for improving oxygen provision in the future. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Members of the public | 1 | 33% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
India | 1 | <1% |
Sweden | 1 | <1% |
Unknown | 203 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 56 | 27% |
Student > Master | 25 | 12% |
Student > Postgraduate | 16 | 8% |
Researcher | 13 | 6% |
Other | 12 | 6% |
Other | 28 | 14% |
Unknown | 56 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 71 | 34% |
Nursing and Health Professions | 36 | 17% |
Biochemistry, Genetics and Molecular Biology | 9 | 4% |
Agricultural and Biological Sciences | 9 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 3% |
Other | 18 | 9% |
Unknown | 56 | 27% |