Title |
Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
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Published in |
Neuropsychiatric Disease and Treatment, November 2017
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DOI | 10.2147/ndt.s148616 |
Pubmed ID | |
Authors |
Kosuke Okazaki, Kazuhiko Yamamuro, Toshifumi Kishimoto |
Abstract |
Antipsychotics are effective for treating schizophrenia, but atypical antipsychotics can cause several adverse side effects including weight gain, hyperprolactinemia, and extrapyramidal symptoms. Moreover, weight gain increases the risk of metabolic diseases. We treated a case of olanzapine-induced weight gain in a 41-year-old man with schizophrenia by switching his medication from olanzapine to asenapine. The weight gain improved after switching the medication, from 80.3 to 75.0 kg, a weight loss of 6.6%, and there was no significant worsening of psychological symptoms or other adverse effects. Asenapine might be effective for treating patients with schizophrenia who experience olanzapine-induced weight gain. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 19% |
Student > Bachelor | 4 | 19% |
Student > Doctoral Student | 2 | 10% |
Other | 1 | 5% |
Unspecified | 1 | 5% |
Other | 2 | 10% |
Unknown | 7 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 2 | 10% |
Nursing and Health Professions | 2 | 10% |
Unspecified | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Other | 3 | 14% |
Unknown | 11 | 52% |