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Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research

Overview of attention for article published in Clinical Interventions in Aging, December 2017
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Title
Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
Published in
Clinical Interventions in Aging, December 2017
DOI 10.2147/cia.s130112
Pubmed ID
Authors

Lennox A Graham, Julius Ngwa, Oyonumo Ntekim, Oludolapo Ogunlana, Saba Wolday, Steven Johnson, Megan Johnson, Chimene Castor, Thomas V Fungwe, Thomas O Obisesan

Abstract

Historically, Blacks have been disproportionately underrepresented in clinical trials. Outcomes associated with low Blacks' participation in research include poor understanding of the predictors and treatment of the disease, increasing health disparities, poor health equity, and suboptimal wellness of the nation as a whole. To address this gap in research participation, we analyzed our recruitment data to identify the most effective strategies for enrolling older Blacks in clinical trials. Data used in these analyses were obtained from 3,266 potential volunteers, ages 50 or older, who completed a Mini-Mental State Exam as part of recruitment and screening for various clinical studies on Alzheimer's disease. In order to determine the most effective strategies for engaging Blacks in clinical research, we used tests of proportion to assess significant differences in recruitment sources, counts, and percentages for optimal recruitment strategies by gender. Finally, we employed regression analyses to confirm our findings. Of the total 3,266 screened, 2,830 Black volunteers were identified for further analysis. Overall, more women than men (73.8% vs 26.2%) participated in our recruitment activities. However, a significantly higher proportion of men than women were engaged through family (3.86% vs 1.30%, p=0.0004) and referral sources (5.89% vs 2.59%, p=0.0005). Compared to other sources for recruitment, we encountered a higher proportion of volunteers at health fairs (42.95%), and through advertisements (14.97%). In our sample, years of education and age did not appear to influence the likelihood of an encounter, screening, and potential participation. Our findings indicate Black men and women in our sample were predominantly recruited from health fairs and through advertisements tailored to their health needs and interests. Conversely, we mostly engaged Black men through family referrals and persons known to them, indicating a need for trust in their decision to engage study personnel and/or participate in clinical trials.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 61 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 18%
Student > Master 9 15%
Student > Bachelor 7 11%
Student > Ph. D. Student 7 11%
Student > Postgraduate 4 7%
Other 6 10%
Unknown 17 28%
Readers by discipline Count As %
Medicine and Dentistry 9 15%
Psychology 7 11%
Nursing and Health Professions 4 7%
Neuroscience 3 5%
Social Sciences 2 3%
Other 10 16%
Unknown 26 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2017.
All research outputs
#20,110,957
of 25,584,565 outputs
Outputs from Clinical Interventions in Aging
#1,393
of 1,962 outputs
Outputs of similar age
#321,877
of 446,259 outputs
Outputs of similar age from Clinical Interventions in Aging
#38
of 51 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,962 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.2. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,259 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.