| Title |
Serum levels of GPER -1 in euthymic bipolar patients
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, March 2018
|
| DOI | 10.2147/ndt.s158822 |
| Pubmed ID | |
| Authors |
Fatma Özlem Orhan, Ergül Belge Kurutaş, Adem Doğaner, Ebru Türker, Safiye Şeyma Taner Özcü, Meltem Güngör, Seyfettin Çakmak |
| Abstract |
Estrogen and its receptors have been suggested as playing a role in the pathogenesis of bipolar disorder (BD). Estrogen functions through the estrogen receptors alpha and beta and the recently discovered G-protein-coupled estrogen receptor-1 (GPER-1). The aim of this study was to evaluate serum GPER-1 levels in euthymic BD patients. The study population consisted of 38 euthymic outpatients meeting the criteria for BD in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and 35 age- and gender-matched healthy controls. Medical histories were obtained and physical examinations and laboratory tests conducted. Serum GPER-1 levels were measured in both patients and controls and found to be significantly higher in the BD patients than in controls. These results were not influenced by the medications in use. The results of this study demonstrated that GPER-1 may play a role in BD pathophysiology. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 15 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 2 | 13% |
| Researcher | 2 | 13% |
| Student > Ph. D. Student | 2 | 13% |
| Unspecified | 1 | 7% |
| Student > Bachelor | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 6 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 27% |
| Neuroscience | 2 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
| Unspecified | 1 | 7% |
| Psychology | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 6 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2018.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,902
of 3,131 outputs
Outputs of similar age
#223,031
of 344,853 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#41
of 76 outputs
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