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COPD: balancing oxidants and antioxidants

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, February 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (62nd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

twitter
3 tweeters
facebook
3 Facebook pages

Citations

dimensions_citation
122 Dimensions

Readers on

mendeley
197 Mendeley
Title
COPD: balancing oxidants and antioxidants
Published in
International Journal of Chronic Obstructive Pulmonary Disease, February 2015
DOI 10.2147/copd.s42414
Pubmed ID
Authors

Bernard Fischer, Judith Voynow, Andrew Ghio

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the most common chronic illnesses in the world. The disease encompasses emphysema, chronic bronchitis, and small airway obstruction and can be caused by environmental exposures, primarily cigarette smoking. Since only a small subset of smokers develop COPD, it is believed that host factors interact with the environment to increase the propensity to develop disease. The major pathogenic factors causing disease include infection and inflammation, protease and antiprotease imbalance, and oxidative stress overwhelming antioxidant defenses. In this review, we will discuss the major environmental and host sources for oxidative stress; discuss how oxidative stress regulates chronic bronchitis; review the latest information on genetic predisposition to COPD, specifically focusing on oxidant/antioxidant imbalance; and review future antioxidant therapeutic options for COPD. The complexity of COPD will necessitate a multi-target therapeutic approach. It is likely that antioxidant supplementation and dietary antioxidants will have a place in these future combination therapies.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 197 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 <1%
Unknown 196 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 40 20%
Student > Master 33 17%
Student > Ph. D. Student 22 11%
Researcher 14 7%
Student > Doctoral Student 13 7%
Other 25 13%
Unknown 50 25%
Readers by discipline Count As %
Medicine and Dentistry 49 25%
Biochemistry, Genetics and Molecular Biology 21 11%
Agricultural and Biological Sciences 20 10%
Nursing and Health Professions 16 8%
Pharmacology, Toxicology and Pharmaceutical Science 13 7%
Other 21 11%
Unknown 57 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2015.
All research outputs
#8,663,236
of 16,623,170 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#833
of 1,925 outputs
Outputs of similar age
#109,719
of 295,323 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#5
of 20 outputs
Altmetric has tracked 16,623,170 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,925 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,323 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.