Title |
Increased expression of retinoic acid-induced gene 1 in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression
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Published in |
Neuropsychiatric Disease and Treatment, February 2015
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DOI | 10.2147/ndt.s72536 |
Pubmed ID | |
Authors |
Johannes Haybaeck, Magdalena Postruznik, Christine L Miller, Jeannette R Dulay, Ida C Llenos, Serge Weis |
Abstract |
Retinoids regulate gene expression in different cells and tissues at the transcriptional level. Retinoic acid transcriptionally regulates downstream regulatory molecules, including enzymes, transcription factors, cytokines, and cytokine receptors. Animal models indicate an involvement of retinoid signaling pathways in the regulation of synaptic plasticity and learning, especially in the hippocampus. Retinoic acid-inducible or induced gene 1 (RAI-1) is induced during neuronal differentiation, and was associated with the severity of the phenotype and response to medication in schizophrenic patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Malaysia | 1 | 3% |
Unknown | 39 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 23% |
Student > Bachelor | 4 | 10% |
Researcher | 4 | 10% |
Student > Ph. D. Student | 4 | 10% |
Other | 3 | 8% |
Other | 7 | 18% |
Unknown | 9 | 23% |
Readers by discipline | Count | As % |
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Neuroscience | 9 | 23% |
Biochemistry, Genetics and Molecular Biology | 7 | 18% |
Medicine and Dentistry | 5 | 13% |
Psychology | 5 | 13% |
Agricultural and Biological Sciences | 4 | 10% |
Other | 2 | 5% |
Unknown | 8 | 20% |