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Cryo-ablation improves anti-tumor immunity through recovering tumor educated dendritic cells in tumor-draining lymph nodes

Overview of attention for article published in Drug Design, Development and Therapy, March 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

twitter
4 tweeters

Citations

dimensions_citation
13 Dimensions

Readers on

mendeley
19 Mendeley
Title
Cryo-ablation improves anti-tumor immunity through recovering tumor educated dendritic cells in tumor-draining lymph nodes
Published in
Drug Design, Development and Therapy, March 2015
DOI 10.2147/dddt.s76592
Pubmed ID
Authors

Shi-Zhong Zhang, Xiao-Zheng He, Shuai Han, Qi-Fu Wang, Yong-Yi Ye, Zhi-Yuan Zhu, Hui-Qing Wang

Abstract

In addition to minimally invasive destruction of tumors, cryo-ablation of tumors to some extent modulated anti-tumor immunity. Cryo-ablated tumors in glioma mice models induced anti-tumor cellular immunologic response which increases the percentage of CD3(+) and CD4(+)T cells in blood as well as natural killer cells. As a crucial role in triggering anti-tumor immunity, dendritic cells (DCs) were educated by tumors to adopt a tolerance phenotype which helps the tumor escape from immune monitoring. This study aims to study whether cryo-ablation could influence the tolerogenic DCs, and influence anti-tumor immunity in tumor-draining lymph nodes (TDLNs).

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 21%
Student > Bachelor 3 16%
Student > Doctoral Student 2 11%
Student > Ph. D. Student 2 11%
Professor 1 5%
Other 2 11%
Unknown 5 26%
Readers by discipline Count As %
Medicine and Dentistry 6 32%
Agricultural and Biological Sciences 2 11%
Veterinary Science and Veterinary Medicine 1 5%
Physics and Astronomy 1 5%
Nursing and Health Professions 1 5%
Other 2 11%
Unknown 6 32%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2015.
All research outputs
#12,919,961
of 22,796,179 outputs
Outputs from Drug Design, Development and Therapy
#632
of 2,083 outputs
Outputs of similar age
#116,226
of 256,542 outputs
Outputs of similar age from Drug Design, Development and Therapy
#30
of 69 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,083 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,542 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.