| Title |
Home-based pulmonary rehabilitation improves clinical features and systemic inflammation in chronic obstructive pulmonary disease patients
|
|---|---|
| Published in |
International Journal of Chronic Obstructive Pulmonary Disease, March 2015
|
| DOI | 10.2147/copd.s76216 |
| Pubmed ID | |
| Authors |
Eloisa Sanches Pereira do Nascimento, Luciana Maria Malosá Sampaio, Fabiana Sobral Peixoto-Souza, Fernanda Dultra Dias, Evelim Leal Freitas Dantas Gomes, Flavia Regina Greiffo, Ana Paula Ligeiro de Oliveira, Roberto Stirbulov, Rodolfo Paula Vieira, Dirceu Costa |
| Abstract |
Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by chronic airflow limitation that leads beyond the pulmonary changes to important systemic effects. COPD is characterized by pulmonary and systemic inflammation. However, increases in the levels of inflammatory cytokines in plasma are found even when the disease is stable. Pulmonary rehabilitation improves physical exercise capacity and quality of life and decreases dyspnea. The aim of this study was to evaluate whether a home-based pulmonary rehabilitation (HBPR) program improves exercise tolerance in COPD patients, as well as health-related quality of life and systemic inflammation. This prospective study was conducted at the Laboratory of Functional Respiratory Evaluation, Nove de Julho University, São Paulo, Brazil. After anamnesis, patients were subjected to evaluations of health-related quality of life and dyspnea, spirometry, respiratory muscle strength, upper limbs incremental test, incremental shuttle walk test, and blood test for quantification of systemic inflammatory markers (interleukin [IL]-6 and IL-8). At the end of the evaluations, patients received a booklet containing the physical exercises to be performed at home, three times per week for 8 consecutive weeks. Around 25 patients were enrolled, and 14 completed the pre- and post-HBPR ratings. There was a significant increase in the walked distance and the maximal inspiratory pressure, improvements on two components from the health-related quality-of-life questionnaire, and a decrease in plasma IL-8 levels after the intervention. The HBPR is an important and viable alternative to pulmonary rehabilitation for the treatment of patients with COPD; it improves exercise tolerance, inspiratory muscle strength, quality of life, and systemic inflammation in COPD patients. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 164 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 30 | 18% |
| Student > Bachelor | 22 | 13% |
| Researcher | 12 | 7% |
| Student > Postgraduate | 11 | 7% |
| Student > Doctoral Student | 11 | 7% |
| Other | 29 | 18% |
| Unknown | 49 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 26% |
| Nursing and Health Professions | 27 | 16% |
| Sports and Recreations | 10 | 6% |
| Biochemistry, Genetics and Molecular Biology | 7 | 4% |
| Agricultural and Biological Sciences | 5 | 3% |
| Other | 14 | 9% |
| Unknown | 58 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2015.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#2,078
of 2,577 outputs
Outputs of similar age
#200,219
of 270,992 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#26
of 30 outputs
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