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Article Metrics

Breast cancer therapy and cardiovascular risk: focus on trastuzumab

Overview of attention for article published in Vascular Health and Risk Management, January 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
3 tweeters

Citations

dimensions_citation
25 Dimensions

Readers on

mendeley
64 Mendeley
Title
Breast cancer therapy and cardiovascular risk: focus on trastuzumab
Published in
Vascular Health and Risk Management, January 2015
DOI 10.2147/vhrm.s69641
Pubmed ID
Authors

Aamer Sandoo, George D Kitas, Amtul R Carmichael

Abstract

Breast cancer is the most common cancer in the UK. Advances in the methods of early diagnosis as well as newer and more effective treatments have led to improvements of disease-free and overall survival over the last decade. Almost one-third of breast cancers present with an aggressive form characterized by increased expression of human epidermal growth receptor 2 (HER2) proteins. A targeted treatment using monoclonal antibodies against HER2 expression such as trastuzumab has been shown to improve survival. Unfortunately, there is a degree of cardiotoxicity associated with these agents, as inhibition of HER2 pathways can also impair cardioprotective pathways. In the present review, we discuss the mechanisms by which trastuzumab might affect vascular homeostasis leading to endothelial dysfunction. We also provide suggestions for future research examining the effects of trastuzumab on the vasculature in breast cancer.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Ecuador 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Student > Bachelor 11 17%
Researcher 9 14%
Student > Postgraduate 4 6%
Student > Ph. D. Student 4 6%
Other 13 20%
Unknown 12 19%
Readers by discipline Count As %
Medicine and Dentistry 25 39%
Agricultural and Biological Sciences 7 11%
Nursing and Health Professions 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 5 8%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 6 9%
Unknown 12 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2017.
All research outputs
#4,787,645
of 9,719,571 outputs
Outputs from Vascular Health and Risk Management
#209
of 456 outputs
Outputs of similar age
#95,087
of 213,062 outputs
Outputs of similar age from Vascular Health and Risk Management
#2
of 6 outputs
Altmetric has tracked 9,719,571 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 456 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.