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Lipid-modifying therapy in the elderly

Overview of attention for article published in Vascular Health and Risk Management, May 2015
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Title
Lipid-modifying therapy in the elderly
Published in
Vascular Health and Risk Management, May 2015
DOI 10.2147/vhrm.s40474
Pubmed ID
Authors

Ian Hamilton-Craig, David Colquhoun, Karam Kostner, Stan Woodhouse, Michael d’Emden

Abstract

Cardiovascular disease (CVD) mortality and morbidity increases with increasing age, largely as a result of increased lifetime exposure as well as increased prevalence of CVD risk factors. Hospitalization for CVD increases by a factor of over 18× for those aged 85+ years versus those aged <30 years. In spite of this, life expectancy continues to increase, and in Australia for people reaching the age of 65 years, it is now 84 years in men and 87 years in women. The number of people for whom lipid management is potentially indicated therefore increases with aging. This is especially the case for secondary prevention and for people aged 65-75 years for whom there is also evidence of benefit from primary prevention. Many people in this age group are not treated with lipid-lowering drugs, however. Even those with CVD may be suboptimally treated, with one study showing treatment rates to fall from ~60% in those aged <50 years to <15% for those aged 85+ years. Treatment of the most elderly patient groups remains controversial partly from the lack of randomized trial intervention data and partly from the potential for adverse effects of lipid therapy. There are many complex issues involved in the decision to introduce effective lipid-lowering therapy and, unfortunately, in many instances there is not adequate data to make evidence-based decisions regarding management. This review summarizes the current state of knowledge of the management of lipid disorders in the elderly and proposes guidelines for management.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
United States 1 2%
Unknown 58 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 15%
Professor 8 13%
Researcher 7 12%
Student > Master 7 12%
Student > Postgraduate 6 10%
Other 13 22%
Unknown 10 17%
Readers by discipline Count As %
Medicine and Dentistry 26 43%
Pharmacology, Toxicology and Pharmaceutical Science 8 13%
Nursing and Health Professions 6 10%
Agricultural and Biological Sciences 3 5%
Social Sciences 2 3%
Other 3 5%
Unknown 12 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2015.
All research outputs
#20,823,121
of 25,584,565 outputs
Outputs from Vascular Health and Risk Management
#663
of 785 outputs
Outputs of similar age
#206,969
of 279,338 outputs
Outputs of similar age from Vascular Health and Risk Management
#14
of 14 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,338 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.