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Cognitive impairment in generalized anxiety disorder revealed by event-related potential N270

Overview of attention for article published in Neuropsychiatric Disease and Treatment, June 2015
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1 X user
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83 Mendeley
Title
Cognitive impairment in generalized anxiety disorder revealed by event-related potential N270
Published in
Neuropsychiatric Disease and Treatment, June 2015
DOI 10.2147/ndt.s84666
Pubmed ID
Authors

Yingxue Yang, Xiating Zhang, Yu Zhu, Yakang Dai, Ting Liu, Yuping Wang

Abstract

Cognitive function in anxiety disorders has been the subject of limited investigation, especially in generalized anxiety disorder (GAD). The purpose of this study was to investigate the cognitive function in subjects with GAD using mismatch-triggered negativity N270. Fifteen medication-free patients with a DSM-IV diagnosis of GAD, and 15 well-matched healthy controls performed a dual-feature delayed matching task while event-related potentials were recorded from their scalp. The GAD group was characterized by the decreased N270 amplitude in the left hemisphere. The smaller N270 amplitude was associated with greater symptoms of anxiety and depression. Since N270 is thought to index cognitive function in different domains, including attention and memory, our results suggest that individuals with GAD have an impaired cognitive function, particularly in selective attention and working memory. These cognitive deficits may have clinical significance in subjects with GAD and should be considered in treatment planning.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 1%
Unknown 82 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 18%
Student > Master 12 14%
Student > Doctoral Student 9 11%
Student > Ph. D. Student 9 11%
Researcher 6 7%
Other 11 13%
Unknown 21 25%
Readers by discipline Count As %
Psychology 26 31%
Medicine and Dentistry 12 14%
Neuroscience 9 11%
Nursing and Health Professions 3 4%
Agricultural and Biological Sciences 2 2%
Other 9 11%
Unknown 22 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2015.
All research outputs
#16,720,137
of 25,371,288 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,719
of 3,132 outputs
Outputs of similar age
#159,109
of 281,402 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#57
of 80 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,402 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.