Title |
Lipidomics in vascular health: current perspectives
|
---|---|
Published in |
Vascular Health and Risk Management, June 2015
|
DOI | 10.2147/vhrm.s54874 |
Pubmed ID | |
Authors |
Genovefa Kolovou, Vana Kolovou, Sophie Mavrogeni |
Abstract |
Identifying the mechanisms that convert a healthy vascular wall to an atherosclerotic wall is of major importance since the consequences may lead to a shortened lifespan. Classical risk factors (age, smoking, obesity, diabetes mellitus, hypertension, and dyslipidemia) may result in the progression of atherosclerotic lesions by processes including inflammation and lipid accumulation. Thus, the evaluation of blood lipids and the full lipid complement produced by cells, organisms, or tissues (lipidomics) is an issue of importance. In this review, we shall describe the recent progress in vascular health research using lipidomic advances. We will begin with an overview of vascular wall biology and lipids, followed by a short analysis of lipidomics. Finally, we shall focus on the clinical implications of lipidomics and studies that have examined lipidomic approaches and vascular health. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 3 | 75% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Finland | 1 | 1% |
Chile | 1 | 1% |
Netherlands | 1 | 1% |
Unknown | 75 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 19 | 24% |
Student > Ph. D. Student | 16 | 21% |
Student > Master | 13 | 17% |
Other | 4 | 5% |
Professor > Associate Professor | 4 | 5% |
Other | 11 | 14% |
Unknown | 11 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 23% |
Biochemistry, Genetics and Molecular Biology | 13 | 17% |
Agricultural and Biological Sciences | 12 | 15% |
Chemistry | 9 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Other | 7 | 9% |
Unknown | 16 | 21% |