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Positioning new pharmacotherapies for COPD

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, July 2015
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Mentioned by

twitter
1 tweeter

Citations

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23 Dimensions

Readers on

mendeley
49 Mendeley
Title
Positioning new pharmacotherapies for COPD
Published in
International Journal of Chronic Obstructive Pulmonary Disease, July 2015
DOI 10.2147/copd.s83758
Pubmed ID
Authors

Igor Barjaktarevic, Anthony Arredondo, Christopher Cooper

Abstract

COPD imposes considerable worldwide burden in terms of morbidity and mortality. In recognition of this, there is now extensive focus on early diagnosis, secondary prevention, and optimizing medical management of the disease. While established guidelines recognize different grades of disease severity and offer a structured basis for disease management based on symptoms and risk, it is becoming increasingly evident that COPD is a condition characterized by many phenotypes and its control in a single patient may require clinicians to have access to a broader spectrum of pharmacotherapies. This review summarizes recent developments in COPD management and compares established pharmacotherapy with new and emerging pharmacotherapies including long-acting muscarinic antagonists, long-acting β-2 sympathomimetic agonists, and fixed-dose combinations of long-acting muscarinic antagonists and long-acting β-2 sympathomimetic agonists as well as inhaled cortiocosteroids, phosphodiesterase inhibitors, and targeted anti-inflammatory drugs. We also review the available oral medications and new agents with novel mechanisms of action in early stages of development. With several new pharmacological agents intended for the management of COPD, it is our goal to familiarize potential prescribers with evidence relating to the efficacy and safety of new medications and to suggest circumstances in which these therapies could be most useful.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Brazil 1 2%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 18%
Researcher 6 12%
Student > Bachelor 5 10%
Other 5 10%
Student > Postgraduate 4 8%
Other 15 31%
Unknown 5 10%
Readers by discipline Count As %
Medicine and Dentistry 27 55%
Pharmacology, Toxicology and Pharmaceutical Science 11 22%
Agricultural and Biological Sciences 2 4%
Economics, Econometrics and Finance 2 4%
Nursing and Health Professions 1 2%
Other 1 2%
Unknown 5 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2015.
All research outputs
#12,430,163
of 15,641,217 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#1,474
of 1,839 outputs
Outputs of similar age
#163,167
of 236,330 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#80
of 100 outputs
Altmetric has tracked 15,641,217 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,839 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,330 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.