| Title |
Folate status in type 2 diabetic patients with and without retinopathy
|
|---|---|
| Published in |
Clinical Ophthalmology, August 2015
|
| DOI | 10.2147/opth.s77538 |
| Pubmed ID | |
| Authors |
Giulia Malaguarnera, Caterina Gagliano, Salvatore Salomone, Maria Giordano, Claudio Bucolo, Antonino Pappalardo, Filippo Drago, Filippo Caraci, Teresio Avitabile, Massimo Motta |
| Abstract |
Folate deficiency is associated with cardiovascular disease, megaloblastic anemia, and with hyperhomocysteinemia. This study has been undertaken to investigate the role of folate status during the progression of the diabetic retinopathy. We measured the plasma levels of homocysteine, folic acid, and red cell folate in 70 diabetic type 2 patients with nonproliferative diabetic retinopathy (NPDR), 65 with proliferative diabetic retinopathy (PDR), 96 without diabetic retinopathy, and 80 healthy subjects used as a control group. We found higher plasma levels of homocysteine in the NPDR group compared to the control group (P<0.001) and in the PDR group compared to control group (P<0.001) and NPDR group (P<0.01). The severity of diabetic retinopathy was associated with lower folic acid and red cell folate levels, and a significant difference was observed between PDR and NPDR groups (P<0.05). The folate status could play a role in the development and progression of diabetic retinopathy. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 2% |
| Unknown | 44 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 13% |
| Researcher | 5 | 11% |
| Student > Postgraduate | 3 | 7% |
| Student > Ph. D. Student | 3 | 7% |
| Lecturer > Senior Lecturer | 2 | 4% |
| Other | 7 | 16% |
| Unknown | 19 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 27% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
| Agricultural and Biological Sciences | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Neuroscience | 2 | 4% |
| Other | 4 | 9% |
| Unknown | 19 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2015.
All research outputs
#16,046,765
of 25,373,627 outputs
Outputs from Clinical Ophthalmology
#1,344
of 3,712 outputs
Outputs of similar age
#146,208
of 276,419 outputs
Outputs of similar age from Clinical Ophthalmology
#25
of 86 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,712 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 58% of its peers.
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We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.