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The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach

Overview of attention for article published in Clinical, Cosmetic and Investigational Dermatology, September 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#29 of 443)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

news
7 news outlets
twitter
7 tweeters
facebook
1 Facebook page
video
3 video uploaders

Citations

dimensions_citation
18 Dimensions

Readers on

mendeley
70 Mendeley
Title
The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach
Published in
Clinical, Cosmetic and Investigational Dermatology, September 2015
DOI 10.2147/ccid.s84903
Pubmed ID
Authors

Diana Crisan, Iulia Roman, Karin Scharffetter-Kochanek, Maria Crisan, Radu Badea

Abstract

Imagistic methods stand as modern, non-invasive, and objective means of assessing the impact of topical cutaneous therapies. This study focuses on the evaluation, by high-frequency ultrasound, of the cutaneous changes induced by topical use of a vitamin C complex at facial level. A vitamin C-based solution/Placebo moisturizer cream was applied at facial level of 60 healthy female subjects according to a predetermined protocol. Ultrasonographic images (Dermascan C, 20 MHz) were taken from zygomatic level initially, at 40 and 60 days after therapy. The following parameters were assessed for every subject: thickness of the epidermis and dermis (mm), the number of low (LEP), medium (MEP), high echogenic pixels (HEP), and the number of LEP in the upper dermis/lower dermis (LEPs/LEPi). LEP decreased significantly in all age categories during and after therapy, but especially in the first 2 age intervals, up to the age of 50 (P=0.0001). MEP and HEP, pixel categories that quantify protein synthesis also had an age-dependent evolution in the study, increasing significantly in all age categories but most of all in the first age interval (P=0.002). Our ultrasonographic data suggest that collagen synthesis increased significantly after topical vitamin C therapy, and is responsible for the increase in MEP and HEP and consequent decrease of the LEP. Our study shows that topically applied vitamin C is highly efficient as a rejuvenation therapy, inducing significant collagen synthesis in all age groups with minimal side effects.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
India 1 1%
Unknown 68 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 17%
Student > Master 11 16%
Researcher 9 13%
Other 8 11%
Student > Ph. D. Student 6 9%
Other 13 19%
Unknown 11 16%
Readers by discipline Count As %
Medicine and Dentistry 23 33%
Agricultural and Biological Sciences 9 13%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Biochemistry, Genetics and Molecular Biology 5 7%
Materials Science 4 6%
Other 10 14%
Unknown 13 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2021.
All research outputs
#423,093
of 17,345,379 outputs
Outputs from Clinical, Cosmetic and Investigational Dermatology
#29
of 443 outputs
Outputs of similar age
#7,635
of 245,314 outputs
Outputs of similar age from Clinical, Cosmetic and Investigational Dermatology
#5
of 15 outputs
Altmetric has tracked 17,345,379 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 443 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,314 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.