| Title |
The rapid effects of budesonide plus formoterol in patients with obstructive airway diseases
|
|---|---|
| Published in |
Drug Design, Development and Therapy, September 2015
|
| DOI | 10.2147/dddt.s90504 |
| Pubmed ID | |
| Authors |
Hulya Bayiz, Sevket Ozkaya, Adem Dirican, Ferah Ece |
| Abstract |
The use of a combination inhaler containing budesonide and formoterol (BUD/FOR) to both maintenance and quick relief therapy has been recommended as an improved method of using inhaled corticosteroid/long-acting β agonist therapy. The aim of this study was to investigate the acute effects of BUD/FOR and testing the availability of BUD/FOR for early reversibility test in patients with airway obstruction. The study was conducted on patients who were admitted to the Department of Pulmonary Medicine, Samsun Medical Park Hospital, Samsun, Turkey. A total of 44 patients were included in the study. The mean age of patients was 48.5±17.3 (range 10-75) years and the male-to-female ratio was 36:8. The pre-bronchodilator pulmonary function test results are as follows: the mean forced vital capacity, 3,025±1,162 mL (76.3%±23.2%); mean forced expiratory volume in 1 second (FEV1), 1,898±725 mL (59.2%±19.1%); mean FEV1/forced vital capacity, 62.8±6.3% (range 42%-70%); mean peak expiratory flow, 3,859±1,779 mL (48.0%±19.7%); and forced expiratory flow 25%-75%, 1,295±486 mL (35.8%±12.3%). The reversibility was positive in 26 (59.1%) patients. The absolute change and percentage of change in FEV1 were 318±228 mL and 17.7%±11.9%, respectively. The patients were divided into two groups according to reversibility (reversible and irreversible) and both groups were compared with changes according to spirometric results. FEV1 values were statistically different between the two groups. The fixed combination of BUD/FOR has rapid bronchodilator effect, and they can be used for early reversibility test. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 5% |
| Unknown | 20 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 29% |
| Student > Ph. D. Student | 3 | 14% |
| Student > Bachelor | 2 | 10% |
| Other | 2 | 10% |
| Student > Doctoral Student | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 6 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 14% |
| Nursing and Health Professions | 3 | 14% |
| Computer Science | 1 | 5% |
| Agricultural and Biological Sciences | 1 | 5% |
| Other | 2 | 10% |
| Unknown | 7 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2016.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Drug Design, Development and Therapy
#1,437
of 2,268 outputs
Outputs of similar age
#203,164
of 276,789 outputs
Outputs of similar age from Drug Design, Development and Therapy
#84
of 133 outputs
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