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The rapid effects of budesonide plus formoterol in patients with obstructive airway diseases

Overview of attention for article published in Drug Design, Development and Therapy, September 2015
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1 tweeter
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14 Mendeley
Title
The rapid effects of budesonide plus formoterol in patients with obstructive airway diseases
Published in
Drug Design, Development and Therapy, September 2015
DOI 10.2147/dddt.s90504
Pubmed ID
Authors

Sevket Ozkaya, Hulya Bayiz, Ferah Ece, Adem Dirican

Abstract

The use of a combination inhaler containing budesonide and formoterol (BUD/FOR) to both maintenance and quick relief therapy has been recommended as an improved method of using inhaled corticosteroid/long-acting β agonist therapy. The aim of this study was to investigate the acute effects of BUD/FOR and testing the availability of BUD/FOR for early reversibility test in patients with airway obstruction. The study was conducted on patients who were admitted to the Department of Pulmonary Medicine, Samsun Medical Park Hospital, Samsun, Turkey. A total of 44 patients were included in the study. The mean age of patients was 48.5±17.3 (range 10-75) years and the male-to-female ratio was 36:8. The pre-bronchodilator pulmonary function test results are as follows: the mean forced vital capacity, 3,025±1,162 mL (76.3%±23.2%); mean forced expiratory volume in 1 second (FEV1), 1,898±725 mL (59.2%±19.1%); mean FEV1/forced vital capacity, 62.8±6.3% (range 42%-70%); mean peak expiratory flow, 3,859±1,779 mL (48.0%±19.7%); and forced expiratory flow 25%-75%, 1,295±486 mL (35.8%±12.3%). The reversibility was positive in 26 (59.1%) patients. The absolute change and percentage of change in FEV1 were 318±228 mL and 17.7%±11.9%, respectively. The patients were divided into two groups according to reversibility (reversible and irreversible) and both groups were compared with changes according to spirometric results. FEV1 values were statistically different between the two groups. The fixed combination of BUD/FOR has rapid bronchodilator effect, and they can be used for early reversibility test.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 21%
Student > Ph. D. Student 3 21%
Student > Bachelor 2 14%
Other 2 14%
Student > Doctoral Student 1 7%
Other 0 0%
Unknown 3 21%
Readers by discipline Count As %
Medicine and Dentistry 3 21%
Nursing and Health Professions 2 14%
Pharmacology, Toxicology and Pharmaceutical Science 2 14%
Computer Science 1 7%
Psychology 1 7%
Other 2 14%
Unknown 3 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2016.
All research outputs
#11,149,539
of 14,054,251 outputs
Outputs from Drug Design, Development and Therapy
#836
of 1,475 outputs
Outputs of similar age
#170,142
of 248,599 outputs
Outputs of similar age from Drug Design, Development and Therapy
#77
of 122 outputs
Altmetric has tracked 14,054,251 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,475 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,599 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.