| Title |
Cigarette smoke is a risk factor for severity and treatment outcome in patients with culture-positive tuberculosis
|
|---|---|
| Published in |
Therapeutics and Clinical Risk Management, October 2015
|
| DOI | 10.2147/tcrm.s87218 |
| Pubmed ID | |
| Authors |
Hsiao-Chi Chuang, Chien-Ling Su, Hui-Chiao Liu, Po-Hao Feng, Kang-Yun Lee, Kai-Jen Chuang, Chun-Nin Lee, Mauo-Ying Bien |
| Abstract |
Smoking has been associated with tuberculosis (TB); however, the effects of smoking on the effectiveness of TB treatment remain unclear. Data were retrieved from case notes and interviews of subjects registered in the TB-reporting system from 2010 to 2012. Study cases were defined as subjects with TB-positive sputum cultures, whereas the controls were defined as subjects with non-TB-related pulmonary diseases. Statistical analyses included logistic regression and multivariate Cox proportional hazard regression models. A total of 245 cases with cultures positive for TB and 114 controls with non-TB-related pulmonary diseases and negative sputum cultures were recruited. Current smokers had the highest failure rate (33%) for TB treatment, and they had the most severe pulmonary lesions based on chest X-ray grading. Current smokers had a 1.36-fold (95% confidence interval 1.03-2.36, P<0.05) higher odds ratio for cultures positive for TB compared with nonsmokers. In subjects with TB-positive cultures, current smoking was associated with an increase in treatment days required for cultures to convert from positive to negative (hazard ratio 1.12, 95% confidence interval 1.03-1.39; P<0.05). Longer periods of treatment may be required for TB patients who are current smokers. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | <1% |
| Unknown | 101 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 16% |
| Student > Master | 11 | 11% |
| Lecturer | 6 | 6% |
| Researcher | 4 | 4% |
| Student > Postgraduate | 4 | 4% |
| Other | 19 | 19% |
| Unknown | 42 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 28% |
| Nursing and Health Professions | 10 | 10% |
| Environmental Science | 4 | 4% |
| Agricultural and Biological Sciences | 4 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 10 | 10% |
| Unknown | 43 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2015.
All research outputs
#15,298,886
of 25,576,275 outputs
Outputs from Therapeutics and Clinical Risk Management
#666
of 1,324 outputs
Outputs of similar age
#140,657
of 287,373 outputs
Outputs of similar age from Therapeutics and Clinical Risk Management
#27
of 53 outputs
Altmetric has tracked 25,576,275 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,324 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,373 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.