↓ Skip to main content

Dove Medical Press

Article Metrics

Candidate genes for COPD: current evidence and research

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, October 2015
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
30 Dimensions

Readers on

mendeley
61 Mendeley
Title
Candidate genes for COPD: current evidence and research
Published in
International Journal of Chronic Obstructive Pulmonary Disease, October 2015
DOI 10.2147/copd.s80227
Pubmed ID
Authors

Sang Do Lee, Woo Jin Kim

Abstract

COPD is a common complex disease characterized by progressive airflow limitation. Several genome-wide association studies (GWASs) have discovered genes that are associated with COPD. Recently, candidate genes for COPD identified by GWASs include CHRNA3/5 (cholinergic nicotine receptor alpha 3/5), IREB2 (iron regulatory binding protein 2), HHIP (hedgehog-interacting protein), FAM13A (family with sequence similarity 13, member A), and AGER (advanced glycosylation end product-specific receptor). Their association with COPD susceptibility has been replicated in multiple populations. Since these candidate genes have not been considered in COPD, their pathological roles are still largely unknown. Herein, we review some evidences that they can be effective drug targets or serve as biomarkers for diagnosis or subtyping. However, more study is required to understand the functional roles of these candidate genes. Future research is needed to characterize the effect of genetic variants, validate gene function in humans and model systems, and elucidate the genes' transcriptional and posttranscriptional regulatory mechanisms.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 23%
Researcher 10 16%
Student > Master 8 13%
Student > Bachelor 5 8%
Student > Doctoral Student 4 7%
Other 7 11%
Unknown 13 21%
Readers by discipline Count As %
Medicine and Dentistry 15 25%
Agricultural and Biological Sciences 10 16%
Biochemistry, Genetics and Molecular Biology 10 16%
Computer Science 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 7 11%
Unknown 15 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2015.
All research outputs
#8,810,900
of 14,054,251 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#1,115
of 1,733 outputs
Outputs of similar age
#152,170
of 283,382 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#58
of 84 outputs
Altmetric has tracked 14,054,251 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,733 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,382 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.