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Recent advances in "smart" delivery systems for extended drug release in cancer therapy

Overview of attention for article published in International Journal of Nanomedicine, August 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

twitter
4 tweeters

Citations

dimensions_citation
85 Dimensions

Readers on

mendeley
178 Mendeley
Title
Recent advances in "smart" delivery systems for extended drug release in cancer therapy
Published in
International Journal of Nanomedicine, August 2018
DOI 10.2147/ijn.s168053
Pubmed ID
Authors

Regina-Veronicka Kalaydina, Komal Bajwa, Bessi Qorri, Alexandria DeCarlo, Myron R Szewczuk

Abstract

Advances in nanomedicine have become indispensable for targeted drug delivery, early detection, and increasingly personalized approaches to cancer treatment. Nanoparticle-based drug-delivery systems have overcome some of the limitations associated with traditional cancer-therapy administration, such as reduced drug solubility, chemoresistance, systemic toxicity, narrow therapeutic indices, and poor oral bioavailability. Advances in the field of nanomedicine include "smart" drug delivery, or multiple levels of targeting, and extended-release drug-delivery systems that provide additional methods of overcoming these limitations. More recently, the idea of combining smart drug delivery with extended-release has emerged in hopes of developing highly efficient nanoparticles with improved delivery, bioavailability, and safety profiles. Although functionalized and extended-release drug-delivery systems have been studied extensively, there remain gaps in the literature concerning their application in cancer treatment. We aim to provide an overview of smart and extended-release drug-delivery systems for the delivery of cancer therapies, as well as to introduce innovative advancements in nanoparticle design incorporating these principles. With the growing need for increasingly personalized medicine in cancer treatment, smart extended-release nanoparticles have the potential to enhance chemotherapy delivery, patient adherence, and treatment outcomes in cancer patients.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 178 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 32 18%
Student > Ph. D. Student 26 15%
Student > Bachelor 26 15%
Researcher 24 13%
Student > Doctoral Student 7 4%
Other 22 12%
Unknown 41 23%
Readers by discipline Count As %
Chemistry 24 13%
Biochemistry, Genetics and Molecular Biology 23 13%
Pharmacology, Toxicology and Pharmaceutical Science 20 11%
Engineering 12 7%
Agricultural and Biological Sciences 11 6%
Other 35 20%
Unknown 53 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2019.
All research outputs
#4,475,444
of 15,329,228 outputs
Outputs from International Journal of Nanomedicine
#439
of 2,932 outputs
Outputs of similar age
#100,554
of 277,525 outputs
Outputs of similar age from International Journal of Nanomedicine
#2
of 27 outputs
Altmetric has tracked 15,329,228 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 2,932 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,525 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.