Title |
Fabrication of ultra-small monolayer graphene quantum dots by pyrolysis of trisodium citrate for fluorescent cell imaging
|
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Published in |
International Journal of Nanomedicine, August 2018
|
DOI | 10.2147/ijn.s168570 |
Pubmed ID | |
Authors |
Guo-Lin Hong, Hai-Ling Zhao, Hao-Hua Deng, Hui-Jing Yang, Hua-Ping Peng, Yin-Huan Liu, Wei Chen |
Abstract |
The preparation and biological applications of ultra-small graphene quantum dots (GQDs) with accurate-controlled size are of great significance. Here in, we report a novel procedure involving pyrolysis of trisodium citrate and subsequent ultrafiltration for fabricating monolayer GQDs with ultra-small lateral size (1.3±0.5 nm). The GQDs exhibit blue photoluminescence with peak position independent of excitation wavelength. The quantum yield of GQDs is measured to be 3.6%, and the average fluorescence lifetime is 2.78 ns. Because of high stability and low toxicity, GQDs are demonstrated to be excellent bioimaging agents. The ultra-small GQDs can not only distribute in the cytoplasm but also penetrate into the nuclei. We ensure that this work will add a new dimension to the application of graphene materials for nanomedicine. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 71 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 16 | 23% |
Researcher | 10 | 14% |
Student > Master | 9 | 13% |
Student > Bachelor | 6 | 8% |
Professor > Associate Professor | 3 | 4% |
Other | 8 | 11% |
Unknown | 19 | 27% |
Readers by discipline | Count | As % |
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Chemistry | 11 | 15% |
Materials Science | 6 | 8% |
Chemical Engineering | 5 | 7% |
Engineering | 5 | 7% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Other | 16 | 23% |
Unknown | 24 | 34% |