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Anti-hyperglycemic activity of selenium nanoparticles in streptozotocin-induced diabetic rats

Overview of attention for article published in International Journal of Nanomedicine, October 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (59th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
2 tweeters
googleplus
1 Google+ user

Citations

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66 Dimensions

Readers on

mendeley
65 Mendeley
Title
Anti-hyperglycemic activity of selenium nanoparticles in streptozotocin-induced diabetic rats
Published in
International Journal of Nanomedicine, October 2015
DOI 10.2147/ijn.s91377
Pubmed ID
Authors

Ahmed Abdel Moneim, Saleh Al-Quraishy, Mohamed A. Dkhil

Abstract

The study was designed to investigate the anti-hyperglycemic activity of selenium nanoparticles (SeNPs) in streptozotocin-induced diabetic rats. Fifty-five mg/kg of streptozotocin was injected in rats to induce diabetes. Animals either treated with SeNPs alone or with insulin (6 U/kg) showed significantly decreased fasting blood glucose levels after 28 days of treatment. The serum insulin concentration in untreated diabetic animals was also enhanced by SeNPs. The results demonstrated that SeNPs could significantly decrease hepatic and renal function markers, total lipid, total cholesterol, triglyceride and low-density lipoprotein cholesterol levels, and glucose-6-phosphatase activity. At the same time, SeNPs increased malic enzyme, hexokinase and glucose-6-phosphate dehydrogenase activity, liver and kidney glycogen contents, and high-density lipoprotein cholesterol levels. In addition, SeNPs were able to prevent the histological injury in the hepatic and renal tissues of rats. However, insulin injection also exhibited a significant improvement in diabetic animals after 28 days of treatment. This study suggests that SeNPs can alleviate hyperglycemia and hyperlipidemia in streptozotocin-induced diabetic rats, possibly by eliciting insulin-mimetic activity.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 26%
Student > Bachelor 10 15%
Student > Ph. D. Student 9 14%
Researcher 5 8%
Student > Postgraduate 2 3%
Other 6 9%
Unknown 16 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 23%
Medicine and Dentistry 9 14%
Agricultural and Biological Sciences 8 12%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Nursing and Health Professions 4 6%
Other 10 15%
Unknown 13 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2015.
All research outputs
#2,411,749
of 6,516,271 outputs
Outputs from International Journal of Nanomedicine
#319
of 1,597 outputs
Outputs of similar age
#80,675
of 207,216 outputs
Outputs of similar age from International Journal of Nanomedicine
#34
of 122 outputs
Altmetric has tracked 6,516,271 research outputs across all sources so far. This one has received more attention than most of these and is in the 61st percentile.
So far Altmetric has tracked 1,597 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,216 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.